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猪链球菌性脊椎间盘炎:2例新病例及文献综述

Streptococcus suis spondylodiscitis: 2 new cases and a literature review.

作者信息

Romay-Lema Eva-María, Ventura-Valcárcel Pablo, Iñiguez-Vázquez Iria, García-Pais María-José, García-Garrote Fernando, Rabuñal-Rey Ramón, Alonso María Pilar, Corredoira-Sánchez Juan

机构信息

Unidad de Enfermedades Infecciosas, Hospital Universitario Lucus Augusti, Lugo, España.

Servicio de Medicina Interna, Hospital Universitario Lucus Augusti, Lugo, España.

出版信息

Enferm Infecc Microbiol Clin (Engl Ed). 2020 Oct 14. doi: 10.1016/j.eimc.2020.08.005.

DOI:10.1016/j.eimc.2020.08.005
PMID:33069490
Abstract

INTRODUCTION

Streptococcus suis (S. suis) infection is poorly described zoonosis in our country, which is related with exposure to pigs or their meat. The most common clinical presentation is meningitis, while spinés involvement is rare.

METHODS

We report 2 cases of S. suis infection and perform a systematic review of the articles published on S. suis spondylodiscitis between January 1994 and May 2020 with the aim of defining the clinical characteristics, predisposing factors and evolution.

RESULTS

17 cases are described, 76.5% males with a mean age of 57.6 years, generally without associated underlying disease. Enolism was a factor present in 17.6%. 70.6% had exposure to pigs or their meat and 20% hand injuries. The mean duration of symptoms was 10.2 days and the most affected segment was the lumbar level. 70.6% had meningitis. All were treated with beta-lactams with an average duration of 53.2 days. There was a recurrence and none died.

CONCLUSION

There are few cases of S. suis spondylodiscitis in the literature. When occurs, it is associated with another type of infection in most cases. They present a good response to medical treatment and a good prognosis.

摘要

引言

猪链球菌感染在我国是一种描述较少的人畜共患病,与接触猪或其肉类有关。最常见的临床表现是脑膜炎,而脊柱受累情况罕见。

方法

我们报告2例猪链球菌感染病例,并对1994年1月至2020年5月间发表的关于猪链球菌性脊椎盘炎的文章进行系统综述,旨在明确其临床特征、易感因素及病情发展。

结果

共描述了17例病例,男性占76.5%,平均年龄57.6岁,一般无相关基础疾病。酗酒是17.6%的病例中存在的一个因素。70.6%的病例有猪或其肉类接触史,20%有手部损伤。症状平均持续时间为10.2天,受累最严重的节段是腰椎水平。70.6%的病例有脑膜炎。所有病例均接受β-内酰胺类药物治疗,平均疗程53.2天。有1例复发,无死亡病例。

结论

文献中猪链球菌性脊椎盘炎病例较少。发病时,大多数情况下与另一种感染相关。它们对药物治疗反应良好,预后良好。

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