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[伤寒沙门菌在伤寒感染发病机制不同阶段的作用]

[The function of Salmonella typhi at different stages in the pathogenesis of typhoid infection].

作者信息

Obgol'ts A A, Demidova A D, Rogatykh N A, Gasheva A Z

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1987 Jun(6):66-71.

PMID:3307243
Abstract

The complex study of the adhesive, colicinogenic and antigenic properties of S. typhi of different origin has revealed that adhesive properties can be observed more frequently in the strains isolated from the blood and bile and are completely absent in the strains isolated from feces. S. typhi strains of various origin do not essentially differ in their sensitivity to colicins and in the capacity for their production. Among the strains isolated from feces and bile, agents in the W-form occur more frequently than among the strains isolated from the blood. Escherichia coli, isolated from typhoid patients and carriers at the moment of the persistence of S. typhi in the body, are characterized by faintly pronounced antagonistic properties, enhanced sensitivity to colicins and rather pronounced hemagglutinating activity.

摘要

对不同来源的伤寒沙门氏菌的黏附、产大肠杆菌素及抗原特性进行的综合研究表明,从血液和胆汁中分离出的菌株更常表现出黏附特性,而从粪便中分离出的菌株则完全没有这种特性。不同来源的伤寒沙门氏菌菌株对大肠杆菌素的敏感性及其产生大肠杆菌素的能力基本没有差异。在从粪便和胆汁中分离出的菌株中,W型菌比从血液中分离出的菌株更常见。在伤寒沙门氏菌在体内持续存在时从伤寒患者和带菌者体内分离出的大肠杆菌,其特点是拮抗特性不明显、对大肠杆菌素的敏感性增强以及血凝活性相当明显。

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