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眼眶神经鞘瘤

Orbital Schwannoma.

作者信息

Chaskes Mark B, Rabinowitz Mindy R

机构信息

Department of Otolaryngology, Head and Neck Surgery, Thomas Jefferson University Hospital, Philadelphia, United States.

出版信息

J Neurol Surg B Skull Base. 2020 Aug;81(4):376-380. doi: 10.1055/s-0040-1713935. Epub 2020 Aug 24.

DOI:10.1055/s-0040-1713935
PMID:33072479
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7561453/
Abstract

Orbital schwannomas are rare neoplasms of the orbit. The presenting symptoms are often nonspecific. Classic imaging characteristics seen on magnetic resonance imaging (MRI) and orbital ultrasound can be useful to help aid in the diagnosis of orbital schwannoma. When diagnosed, the goal of treatment is complete surgical excision. The location of the tumor within the orbit dictates which surgical approach would provide the best exposure. When complete excision is achieved, recurrence rates are very low. This article addresses the etiology, patient population, presentation, natural history, and differential diagnosis of orbital schwannomas. Imaging characteristics and histopathologic subtypes are reviewed. Treatment goals, approaches, and specialties involved in the management of these patients is discussed. Finally, a representative case is presented.

摘要

眼眶神经鞘瘤是眼眶罕见的肿瘤。其表现症状通常不具有特异性。磁共振成像(MRI)和眼眶超声显示的典型影像学特征有助于眼眶神经鞘瘤的诊断。确诊后,治疗目标是完整手术切除。肿瘤在眼眶内的位置决定了哪种手术入路能提供最佳暴露。实现完整切除后,复发率很低。本文探讨眼眶神经鞘瘤的病因、患者群体、表现、自然病史及鉴别诊断。回顾其影像学特征和组织病理学亚型。讨论这些患者管理中的治疗目标、方法及涉及的专业领域。最后展示一个典型病例。

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本文引用的文献

1
Imaging characteristics and surgical management of orbital neurilemmomas.眼眶神经鞘瘤的影像学特征与手术治疗
Int J Ophthalmol. 2019 Jul 18;12(7):1108-1115. doi: 10.18240/ijo.2019.07.09. eCollection 2019.
2
Head and Neck Schwannomas: A Surgical Challenge-A Series of 5 Cases.头颈部神经鞘瘤:一项手术挑战——5例系列报道
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Orbital Schwannoma With Atypical Presentation.具有非典型表现的眼眶神经鞘瘤。
J Craniofac Surg. 2018 May;29(3):e224-e226. doi: 10.1097/SCS.0000000000004177.
4
Schwannoma of the Orbit.眼眶神经鞘瘤
Arch Craniofac Surg. 2015 Aug;16(2):67-72. doi: 10.7181/acfs.2015.16.2.67. Epub 2015 Aug 11.
5
Orbital Schwannoma: Radiographic and Histopathologic Correlation in 15 Cases.眼眶神经鞘瘤:15例的影像学与组织病理学对照研究
Ophthalmic Plast Reconstr Surg. 2018 Mar/Apr;34(2):162-167. doi: 10.1097/IOP.0000000000000900.
6
"Round-the-Clock" Surgical Access to the Orbit.全天候眼眶手术通道
J Neurol Surg B Skull Base. 2015 Feb;76(1):12-24. doi: 10.1055/s-0033-1360580. Epub 2014 Sep 2.
7
Orbital tumors: operative and therapeutic strategies.眼眶肿瘤:手术及治疗策略
Facial Plast Surg. 2014 Oct;30(5):570-7. doi: 10.1055/s-0034-1395210. Epub 2014 Nov 14.
8
Orbital schwannoma: a clinicopathologic study.眼眶神经鞘瘤:一项临床病理研究。
Int Ophthalmol. 2015 Aug;35(4):481-6. doi: 10.1007/s10792-014-9973-1. Epub 2014 Jul 23.
9
Clinico-Radiological Spectrum and Management of Orbital Schwannomas: A Tertiary Care Institute Study.眼眶神经鞘瘤的临床-放射学特征与治疗:一家三级医疗机构的研究
Orbit. 2013 May 10. doi: 10.3109/01676830.2013.788661.
10
Recurrent orbital schwannomas: clinical course and histopathologic correlation.复发性眼眶神经鞘瘤:临床经过与组织病理学相关性。
BMC Ophthalmol. 2012 Aug 31;12:44. doi: 10.1186/1471-2415-12-44.