Department of Rehabilitation, Józef Piłsudski University of Physical Education, Warsaw, Poland.
Center of Functional Rehabilitation Orthos, Warsaw, Poland.
J Mother Child. 2020 Jul 29;24(1):24-32. doi: 10.34763/jmotherandchild.2020241.1935.000003.
Alternating hemiplegia of Childhood (AHC) is a rare disease manifested by transient episodes of hemiplegia and other neurological disorders. Delayed motor development has been reported in patients with AHC, but detailed features of the motor impairment have not been described so far.
The aim of the study was to evaluate gross motor function between attacks in a group of Polish patients with AHC.
The interictal gross motor function was assessed using the Gross Motor Function AHC scale, which consisted of 41 motor tasks. The study group consisted of 10 patients with AHC older than 2 years of age. The control group consisted of 30 age- and gender-matched subjects. The results achieved in each of the 41 tasks by the study subjects were compared to the results obtained with controls using the non-parametric Mann-Whitney U-test. In tasks 38-41, mean times were compared between the study subjects and controls.
The study revealed gross motor function impairment in patients with AHC. The greatest differences compared to controls concerned such skills as standing on toes, walking on toes, walking on heels, as well as running and hopping on one leg and on alternate legs. Significant impairment of the motor function of the upper limbs was also found.
The study confirmed motor function impairment between attacks in patients with AHC. The study findings may indicate the need to introduce individualised physiotherapy management of patients with AHC.
儿童交替性偏瘫（AHC）是一种罕见的疾病，表现为短暂的偏瘫和其他神经障碍发作。AHC 患者的运动发育迟缓已有报道，但迄今尚未描述运动障碍的详细特征。
本研究旨在评估一组波兰 AHC 患者发作间期的粗大运动功能。
使用 AHC 粗大运动功能量表评估发作间期的粗大运动功能，该量表由 41 项运动任务组成。研究组由 10 名年龄大于 2 岁的 AHC 患者组成。对照组由 30 名年龄和性别匹配的受试者组成。使用非参数 Mann-Whitney U 检验比较研究对象在 41 项任务中的每项任务的结果与对照组的结果。在任务 38-41 中，比较研究对象和对照组的平均时间。
研究显示 AHC 患者的粗大运动功能受损。与对照组相比，最大的差异涉及到脚趾站立、脚趾行走、脚跟行走、单腿和交替腿跑步和跳跃等技能。上肢运动功能也明显受损。
本研究证实了 AHC 患者发作间期的运动功能障碍。研究结果可能表明需要为 AHC 患者制定个体化的物理治疗管理。
