Int J Gynecol Pathol. 2021 Sep 1;40(5):470-476. doi: 10.1097/PGP.0000000000000723.
Extraskeletal myxoid chondrosarcoma of the vulva is a very rare tumor, with less than 10 cases reported in the literature. We report a case of a 45-yr-old woman with extraskeletal myxoid chondrosarcoma of the vulva confirmed by EWSR1 fluorescence in situ hybridization. Given the unusual site and prominent myxoid morphology, a broad differential diagnosis and a variety of ancillary testing was required. This article aims to review extraskeletal myxoid chondrosarcoma of the vulva, the differential diagnosis of a myxoid spindle cell neoplasm of the vulva, and the diagnostic importance of immunohistochemistry and EWSR1 fluorescence in situ hybridization.
外阴部骨外黏液样软骨肉瘤非常罕见，文献中报道的病例不足 10 例。我们报告了 1 例 45 岁女性外阴部骨外黏液样软骨肉瘤病例，该病例通过 EWSR1 荧光原位杂交得到证实。鉴于该肿瘤发生的不常见部位和显著黏液样形态，需要进行广泛的鉴别诊断和各种辅助检查。本文旨在回顾外阴部骨外黏液样软骨肉瘤、外阴部黏液样梭形细胞肿瘤的鉴别诊断，以及免疫组织化学和 EWSR1 荧光原位杂交的诊断意义。
