Whitfield Jamie, Harris Roger C, Broad Elizabeth M, Patterson Alison K, Ross Megan L R, Shaw Gregory, Spriet Lawrence L, Burke Louise M
Exercise and Nutrition Research Program, Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, VIC 3000, Australia.
Junipa Ltd, Newmarket, Suffolk, CB8 8HD, UK.
Appl Physiol Nutr Metab. 2021 Mar;46(3):280-283. doi: 10.1139/apnm-2020-0692. Epub 2020 Oct 19.
This study determined if supplementation with pantothenic acid (PA) for 16 weeks could increase skeletal muscle coenzyme A (CoASH) content and exercise performance. Trained male cyclists ( = 14) were matched into control or PA (6 g·day) groups. At 0, 4, 8, and 16 weeks, subjects performed an incremental time to exhaustion cycle with muscle biopsies taken prior to and following exercise. Prolonged PA supplementation did not change skeletal muscle CoASH and acetyl-CoA contents or exercise performance. Supplementation with pantothenic acid for 16 weeks had no effect on skeletal muscle CoASH and acetyl-CoA content or exercise performance in trained male cyclists.
本研究旨在确定补充泛酸（PA）16周是否能增加骨骼肌辅酶A（CoASH）含量和运动表现。将训练有素的男性自行车运动员（n = 14）匹配分为对照组或PA（6 g·天）组。在0、4、8和16周时，受试者进行递增力竭时间的骑行测试，并在运动前后采集肌肉活检样本。长期补充PA并未改变骨骼肌CoASH和乙酰辅酶A含量或运动表现。在训练有素的男性自行车运动员中，补充泛酸16周对骨骼肌CoASH和乙酰辅酶A含量或运动表现没有影响。
