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[楚瓦什亚人群社会人口学群体中阻塞性睡眠呼吸暂停的危险因素]

[Risk factors for obstructive sleep apnea in socio-demographic groups of the population of Chuvashia].

作者信息

Golenkov A V, Kurakina N G, Vecherkina M I, Naumova T V, Filonenko A V

机构信息

Ulyanov Chuvash State University, Cheboksary, Russia.

Republican Narcological Dispensary of the Ministry of Health of Chuvashia, Cheboksary, Russia.

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2020;120(9. Vyp. 2):74-79. doi: 10.17116/jnevro202012009274.

Abstract

OBJECTIVE

To study risk factors (RF) of obstructive sleep apnea syndrome (OSAS) in the socio-demographic groups of the population of Chuvashia.

MATERIALS AND METHODS

An anonymous survey included 2161 residents of Chuvashia (1007 men, 1154 women), aged from 18 to 70 years, average 36.5±13.8 years). Of all included people, 1547 (71.6%) lived in urban settlements, 614 (28.4%) in rural settlements. Exclusion criteria were those under the age of 18 and over 70. Body mass index (BMI) of more than 35 kg/m, neck circumference of more than 43 cm for men or more than 37 cm for women, snoring, fatigue/drowsiness during the day, respiratory arrest in sleep and high blood pressure (BP) were considered as SOAS RF. The likelihood of OSAS was determined by the Lausanne NoSAS (Neck circumference, Obesity, Snoring, Age, Sex) test.

RESULTS

RF OSAS were present in 63.4% of respondents. 2.4% of respondents had a BMI of more than 35 kg/m, 162% had a large neck circumference. Snoring was detected in 24.4%, fatigue/drowsiness during the day in 42.2%, respiratory arrest in sleep in 8.1%, increased BP in 19.7%. In men, compared with women, the number of respondents with a high BMI, snoring, and respiratory failure in a dream was significantly larger; women with a large neck size and complaints of fatigue/drowsiness prevailed. The rural residents had more RF OSAS, including higher BMI, large neck circumference and snoring. The probability of OSAS according to the NoSAS score was 13.65%, including 21.35% of men and 6.93% of women, 11.38% of urban- and 19.38% of rural residents. Multivariate regression analysis showed that the OSAS prediction model included gender, age, BMI, the RF sum of four questions from the questionnaire, neck circumference and level of education with a probability of 99.99%.

CONCLUSION

RF OSAS are widespread in the population of Chuvashia, which requires intensification of preventive measures to minimize them and the development of somnological service in the Republic.

摘要

目的

研究楚瓦什亚人口社会人口群体中阻塞性睡眠呼吸暂停综合征(OSAS)的危险因素(RF)。

材料与方法

一项匿名调查纳入了2161名楚瓦什亚居民(1007名男性,1154名女性),年龄在18至70岁之间,平均年龄为36.5±13.8岁)。在所有纳入的人群中,1547人(71.6%)居住在城市定居点,614人(28.4%)居住在农村定居点。排除标准为年龄在18岁以下和70岁以上。体重指数(BMI)超过35kg/m²、男性颈围超过43cm或女性颈围超过37cm、打鼾、白天疲劳/嗜睡、睡眠呼吸暂停和高血压(BP)被视为OSAS的RF。OSAS的可能性通过洛桑NoSAS(颈围、肥胖、打鼾、年龄、性别)测试来确定。

结果

63.4%的受访者存在OSAS的RF。2.4%的受访者BMI超过35kg/m²,16.2%的受访者颈围较大。24.4%的人检测出打鼾,42.2%的人白天有疲劳/嗜睡,8.1%的人睡眠呼吸暂停,19.7%的人血压升高。与女性相比,男性中BMI高、打鼾和睡眠中呼吸衰竭的受访者数量明显更多;颈围大且有疲劳/嗜睡主诉的女性占多数。农村居民的OSAS的RF更多,包括更高的BMI、更大的颈围和打鼾。根据NoSAS评分,OSAS的概率为13.65%,其中男性为21.35%,女性为6.93%,城市居民为11.38%,农村居民为19.38%。多因素回归分析表明,OSAS预测模型包括性别、年龄、BMI、问卷中四个问题的RF总和、颈围和教育程度,概率为99.99%。

结论

OSAS的RF在楚瓦什亚人口中广泛存在,这需要加强预防措施以将其降至最低,并在该共和国发展睡眠医学服务。

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