Virmani R, Robinowitz M, Geer J C, Breslin P P, Beyer J C, McAllister H A
Arch Pathol Lab Med. 1987 Oct;111(10):972-6.
To confirm earlier studies of a high prevalence of coronary atherosclerosis in combat casualties of the Korean and Vietnam wars, we examined previously uncut coronary arteries from the hearts of 94 American male combat casualties (mean age, 20.5 years) from the Korean War using computerized planimetry and microscopic evaluation. Six (6.4%) men had severe atherosclerosis (75% to 90% cross-sectional area luminal narrowing) in one or more coronary arteries; five of the six had fibrous plaques, and one had a complicated plaque. Our prevalence is similar to that reported previously (5%). Therefore, to determine whether the decrease in the incidence of severe coronary atherosclerosis today is the result of decreased plaque formation in the young, we will need to examine at least 772 men to detect a 50% decline with 85% to 90% confidence.
为了证实早期关于朝鲜战争和越南战争战斗伤亡人员中冠状动脉粥样硬化高患病率的研究，我们使用计算机化平面测量法和显微镜评估，检查了94名朝鲜战争时期美国男性战斗伤亡人员（平均年龄20.5岁）心脏中先前未切开的冠状动脉。6名（6.4%）男性在一条或多条冠状动脉中患有严重动脉粥样硬化（管腔横截面积狭窄75%至90%）；6人中5人有纤维斑块，1人有复杂斑块。我们的患病率与先前报道的（5%）相似。因此，为了确定如今严重冠状动脉粥样硬化发病率的下降是否是年轻人斑块形成减少的结果，我们至少需要检查772名男性，才能在85%至90%的置信度下检测到50%的下降。
