Thomas R L, Hess L W, Johnson T R
Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, School of Medicine, Bethesda, Maryland.
Am J Perinatol. 1987 Oct;4(4):293-9. doi: 10.1055/s-2007-999794.
Two cases of skeletal dysplasia with limb-shortening abnormalities are presented. In association with the skeletal abnormalities, gross hydramnios was noted. A review of the existing literature reveals that coexistent fetal skeletal dysplasia and hydramnios have an extremely poor prognosis, especially in the nonachondroplastic patient with singleton fetus. The two cases presented here and the accompanying review emphasize the importance of recognizing this association in providing appropriate counseling to parents.
本文报告了两例伴有肢体缩短异常的骨骼发育不良病例。与骨骼异常相关的是，发现有严重羊水过多。对现有文献的回顾显示，胎儿骨骼发育不良与羊水过多并存的预后极差，尤其是对于单胎非软骨发育不全的患者。本文介绍的这两个病例以及相关综述强调了在为父母提供适当咨询时认识到这种关联的重要性。
