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异丙肾上腺素致倾斜试验中冠状动脉痉挛伴 ST 段抬高。

Isoproterenol Causing Coronary Vasospasm and ST Elevations During Tilt Table Testing.

机构信息

Ross University, Miramar, FL, USA.

Kern Medical Center-UCLA, Bakersfield, CA, USA.

出版信息

J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620966862. doi: 10.1177/2324709620966862.

Abstract

Syncope is a sudden but reversible brief loss of consciousness secondary to an acute reduction of cerebral perfusion. Reflex syncope denotes neurologically mediated syncope, which includes vasovagal, carotid sinus syndrome, and other situational syncope. The most frequent form of syncope is vasovagal, which is triggered by emotional stress or prolonged standing, and may be diagnosed with the tilt table test. A thorough investigation of syncope is necessary as serious cardiovascular disorders may also be a cause. A tilt table test is a widely used tool utilized by clinicians to diagnose vasovagal syncope and is sometimes augmented with isoproterenol, a β-sympathomimetic that acts on the heart. This report seeks to explain a case of a 48-year-old previously healthy woman who experienced inferior wall ST elevations during tilt table test supplemented with isoproterenol. There is reason to believe that the results of this patient's tilt table test were due to vasovagal syncope in conjunction with right coronary artery vasospasm.

摘要

晕厥是一种突发但可逆转的短暂意识丧失,继发于急性脑灌注减少。反射性晕厥表示神经介导的晕厥,包括血管迷走性晕厥、颈动脉窦综合征和其他情境性晕厥。最常见的晕厥形式是血管迷走性晕厥,由情绪压力或长时间站立引起,可通过倾斜试验进行诊断。晕厥的全面调查是必要的,因为严重的心血管疾病也可能是病因。倾斜试验是临床医生常用的一种工具,用于诊断血管迷走性晕厥,有时可辅以异丙肾上腺素,这是一种作用于心脏的β拟交感神经药。本报告旨在解释一例 48 岁既往健康的女性,在倾斜试验中补充异丙肾上腺素时出现下壁 ST 段抬高。有理由认为,该患者倾斜试验的结果是由于血管迷走性晕厥和右冠状动脉血管痉挛共同作用的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/471a/7594226/3e81a1dbf942/10.1177_2324709620966862-fig1.jpg

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