Egeli Bugra Han, Ugurlu Serdal
Medical Doctor; Cerrahpasa Medical Faculty, University of Istanbul-Cerrahpasa, Istanbul, Turkey.
Professor: Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul-Cerrahpasa, Istanbul, Turkey.
QJM. 2020 Oct 20. doi: 10.1093/qjmed/hcaa291.
As the inflammation research improves year by year, so does our understanding of the autoinflammatory conditions. Over the past years, the number of monogenic autoinflammatory conditions snowballed thanks to our understanding of basic immunology and genetics. Familial Mediterranean Fever (FMF), being the entrance to this fascinating world, still has clinical relevance as it enables us to understand our approach to these patients, treatment modalities, and pathological mechanisms. This review can be used as a tool for clinicians already working with FMF patients to update themselves on recent scientific literature.
随着炎症研究逐年进步，我们对自身炎症性疾病的理解也不断加深。在过去几年里，由于我们对基础免疫学和遗传学的了解，单基因自身炎症性疾病的数量迅速增加。家族性地中海热（FMF）作为进入这个迷人领域的入口，仍然具有临床相关性，因为它使我们能够理解对这些患者的治疗方法、治疗方式和病理机制。这篇综述可以作为临床医生的工具，帮助他们了解最新科学文献，以便更好地治疗FMF患者。
