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青少年时期接受减重手术后 5 年的年轻人的抑郁、焦虑和自杀意念。

Depression, anxiety, and suicidal ideation in young adults 5 years after undergoing bariatric surgery as adolescents.

机构信息

Childhood Obesity Unit, Skåne University Hospital, Malmö, Sweden.

Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

出版信息

Eat Weight Disord. 2021 May;26(4):1211-1221. doi: 10.1007/s40519-020-01024-0. Epub 2020 Oct 20.

Abstract

PURPOSE

Metabolic and bariatric surgery (MBS) is increasingly used in adolescents. The aim was to explore symptoms of depression and anxiety in young adults over 5 years' follow-up after undergoing MBS.

METHODS

Beck Depression Inventory-2 and the Beck Anxiety Inventory were used to assess symptoms of depression and anxiety in 62 patients 1, 2, and 5 years after having Roux-en-Y gastric bypass at 13-18 years of age. Mental health, eating-related problems, and weight outcomes were tested for association with suicidal ideation at the 5-year follow-up.

RESULTS

At the 5-year follow-up, the mean score for depression was 11.4 (± 12.4), indicating minimal symptoms of depression. The mean score for anxiety was 12.82 (± 11.50), indicating mild anxiety symptoms. Still, several participants reported moderate or severe symptoms of depression (26%) and anxiety (32%). Women reported more symptoms than men (P = 0.03 and 0.04). No significant changes were found in self-reported symptoms of depression and anxiety between the 1-year and the 5-year follow-up (P = 0.367 and 0.934). Suicidal ideation was reported by 16% at the 5-year follow-up. Participants reporting suicidal ideation had lost significantly less excess weight than participants without suicidal ideation (P = 0.009).

CONCLUSION

Five years after adolescent MBS, a substantial minority still struggles with mental health issues, and women are more burdened than men. Our results indicate an association between less optimal weight loss and suicidal ideation 5 years after MBS. The findings emphasize the importance of offering long-term follow-up and mental health treatment several years after MBS.

LEVEL OF EVIDENCE

Level III, cohort study.

CLINICAL TRIAL REGISTRATION

The study is registered with ClinicalTrials.gov (NCT00289705). First posted February 10, 2006.

摘要

目的

代谢和减肥手术(MBS)在青少年中的应用日益增多。本研究旨在探讨青少年接受 MBS 治疗 5 年后,通过贝克抑郁量表 2 项(BDI-2)和贝克焦虑量表(BAI)评估,其抑郁和焦虑症状的变化。

方法

在 13-18 岁接受 Roux-en-Y 胃旁路术的 62 例患者中,1、2 和 5 年后使用贝克抑郁量表 2 项(BDI-2)和贝克焦虑量表(BAI)评估其抑郁和焦虑症状。在 5 年随访时,测试心理健康、与饮食相关的问题和体重结果与自杀意念的相关性。

结果

在 5 年随访时,抑郁的平均得分为 11.4(±12.4),表明有轻微的抑郁症状。焦虑的平均得分为 12.82(±11.50),表明有轻度焦虑症状。然而,仍有部分患者报告有中度或重度抑郁(26%)和焦虑(32%)。女性报告的症状比男性多(P=0.03 和 0.04)。1 年和 5 年随访之间,自我报告的抑郁和焦虑症状没有明显变化(P=0.367 和 0.934)。在 5 年随访时,有 16%的患者报告有自杀意念。报告有自杀意念的患者与没有自杀意念的患者相比,体重减轻明显较少(P=0.009)。

结论

在青少年 MBS 治疗后 5 年,仍有相当一部分人存在心理健康问题,女性的负担比男性更重。我们的结果表明,MBS 治疗后 5 年,体重减轻不理想与自杀意念有关。这些发现强调了在 MBS 治疗后多年提供长期随访和心理健康治疗的重要性。

证据水平

三级,队列研究。

临床试验注册

本研究在 ClinicalTrials.gov 注册(NCT00289705)。首次于 2006 年 2 月 10 日发布。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04bf/8062317/cbc72bf90fbf/40519_2020_1024_Fig1_HTML.jpg

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