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[髋部脆性骨折一年后死亡的预后因素。阿诺亚髋部研究]

[Prognostic factors of mortality one year after a hip fragility fracture. Anoia hip study].

作者信息

Duaso Enric, Gamboa-Arango Andrés, Formiga Francesc, Marimón Patrícia, Salgado Maria Teresa, Murga Victor, Lumbreras Célia, Tarrida Anna

机构信息

Unidad Geriátrica de Agudos. Servicio de Geriatría. Hospital de Igualada, Igualada, Barcelona.

Unidad Geriátrica de Agudos. Servicio de Geriatría. Hospital de Igualada, Igualada, Barcelona.

出版信息

Rev Esp Geriatr Gerontol. 2021 Jan-Feb;56(1):18-23. doi: 10.1016/j.regg.2020.09.002. Epub 2020 Oct 17.

DOI:10.1016/j.regg.2020.09.002
PMID:33081979
Abstract

INTRODUCTION

Most of the patients who had a hip fragility fracture are characterized by advanced age, frailty, multimorbidity and high mortality rate into the first year. Our aim is to describe the prognostic factors of mortality one year after a hip fragility fracture.

MATERIAL AND METHODS

Observational prospective study. During the study period we included patients older than 69 years with hip fragility fracture who were admitted to the Acute Geriatric Unit.

RESULTS

We have followed 364 patients, 100 of them died (27.5%). The independent prognostic factors of mortality one year after a hip fragility fracture had been: have a less basis score in Lawton and Brody Scale 0.603 (0.505-0.721) (p< 0.001); have a higher score in Charlson Comorbidity Index 2.332 (1.308-4.157) p = 0.04); have a surgical waiting time ≥ 3 days 3.013 (1.330-6.829) p = 0.008); finding hydroelectrolytic disorders and/or deterioration of glomerular filtration 1.212 (1.017-1.444) p = 0.031) during hospital stay; discriminatory capacity of the area under the curve (AUC) (± 95%): 0.888 (0.880-0.891).

CONCLUSIONS

Prognostic predictors of mortality at one year after a hip fragility fracture are those variables that reflect a worse state of health, complications during hospital stay and a longer surgical waiting time.

摘要

引言

大多数髋部脆性骨折患者具有高龄、身体虚弱、多种疾病并存以及第一年死亡率高的特点。我们的目的是描述髋部脆性骨折一年后死亡率的预后因素。

材料与方法

前瞻性观察研究。在研究期间,我们纳入了69岁以上因髋部脆性骨折入住急性老年病科的患者。

结果

我们随访了364例患者,其中100例死亡(27.5%)。髋部脆性骨折一年后死亡率的独立预后因素为:在Lawton和Brody量表中基础评分较低0.603(0.505 - 0.721)(p < 0.001);Charlson合并症指数得分较高2.332(1.308 - 4.157)p = 0.04);手术等待时间≥3天3.013(1.330 - 6.829)p = 0.008);住院期间发现水电解质紊乱和/或肾小球滤过功能恶化1.212(1.017 - 1.444)p = 0.031);曲线下面积(AUC)的鉴别能力(±95%):0.888(0.880 - 0.891)。

结论

髋部脆性骨折一年后死亡率的预后预测因素是那些反映健康状况较差、住院期间并发症以及手术等待时间较长的变量。

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