Strauss J H, Ballard J O, Chamlian D
Int J Gynaecol Obstet. 1978;16(3):225-7. doi: 10.1002/j.1879-3479.1978.tb00431.x.
A gravida with intrauterine fetal death who developed progressive chronic consumption coagulopathy was treated with heparin. When serial fibrinogen levels fell below 100 mg% and the prothrombin time was significantly prolonged, intravenously injected heparin corrected hypofibrinogenemia. A safe delivery followed administration of oxytocin. The authors emphasize the infrequent need for heparin therapy in the majority of cases of the intrauterine fetal death syndrome. Therapeutic guidelines for its use in selected cases are reviewed.
一名怀有宫内死胎并发展为进行性慢性消耗性凝血病的孕妇接受了肝素治疗。当连续纤维蛋白原水平降至100mg%以下且凝血酶原时间显著延长时，静脉注射肝素纠正了低纤维蛋白原血症。在使用催产素后实现了安全分娩。作者强调，在大多数宫内死胎综合征病例中，肝素治疗的需求并不常见。本文回顾了在特定病例中使用肝素的治疗指南。
