Key Lab of Health Technology Assessment of Ministry of Health, School of Public Health, Fudan University, 130 Dong-An Road, Shanghai, 200032, China.
Minhang Institute, School of Public Health, Fudan University, Shanghai, 201100, China.
Sci Rep. 2020 Oct 20;10(1):17746. doi: 10.1038/s41598-020-74706-5.
This study aims to investigate the serial multiple mediation of physical activity and perceived stress in the relationship between individual social capital and quality of life (QOL) in breast cancer survivors (BCSs). This study was conducted among 520 BCSs between March and April 2017 in Shanghai, China. Data were collected using the Individual Social Capital Scale, the Health-Promoting Lifestyle Profile-II, the Perceived Stress Scale-14 and the EORTC QLQ-C30. Ordinary least-squares regression and the bootstrap method was used to test the significance of the serial multiple mediation model. The serial-multiple mediations of physical activity and perceived stress were found significant in the relationship of QOL with all five dimensions of individual social capital. The separate mediations of two single mediating variables were found significant in the relationship of QOL with control over life and feeling about the community. In the relationship of QOL with social participation, social network and social support, the separate mediation of physical activity was significant, while the separate mediation of perceived stress was not significant. A multidisciplinary team approach and a variety of delivery systems are needed to address the social, physical and psychological issues for improving QOL among BCSs.
本研究旨在探讨体力活动和感知压力在个体社会资本与乳腺癌幸存者(BCSs)生活质量(QOL)之间关系中的序列多重中介作用。本研究于 2017 年 3 月至 4 月在中国上海对 520 名 BCS 进行。使用个体社会资本量表、健康促进生活方式量表-II、感知压力量表-14 和 EORTC QLQ-C30 收集数据。使用普通最小二乘法回归和自举法检验序列多重中介模型的显著性。体力活动和感知压力的序列多重中介作用在 QOL 与个体社会资本的所有五个维度之间的关系中具有显著性。两个单一中介变量的单独中介作用在 QOL 与生活控制和社区感觉的关系中具有显著性。在 QOL 与社会参与、社会网络和社会支持的关系中,体力活动的单独中介作用显著,而感知压力的单独中介作用不显著。需要多学科团队方法和多种交付系统来解决社会、身体和心理问题,以提高 BCSs 的生活质量。