The Lazarus effect of very high-dose intravenous anakinra in severe non-familial CNS-HLH.
作者信息
Kavirayani Akhila, Charlesworth James E G, Segal Shelley, Kelly Dominic, Wilson Shaun, Qureshi Amrana, Blanco Esther, Weitz James, O'Shea Deirdre, Bailey Kathryn
机构信息
Paediatric Rheumatology, Oxford University Hospitals NHS, Foundation Trust, Oxford, UK.
Oxford University Clinical Academic Graduate School, University of Oxford and Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
出版信息
Lancet Rheumatol. 2020 Dec;2(12):e736-e738. doi: 10.1016/S2665-9913(20)30361-1. Epub 2020 Oct 15.
Abstract
摘要
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Silencing the cytokine storm: the use of intravenous anakinra in haemophagocytic lymphohistiocytosis or macrophage activation syndrome.抑制细胞因子风暴：静脉注射阿那白滞素在噬血细胞性淋巴组织细胞增生症或巨噬细胞活化综合征中的应用
Lancet Rheumatol. 2020 Jun;2(6):e358-e367. doi: 10.1016/S2665-9913(20)30096-5. Epub 2020 May 4.
2
How to Treat Involvement of the Central Nervous System in Hemophagocytic Lymphohistiocytosis?如何治疗噬血细胞性淋巴组织细胞增生症的中枢神经系统受累？
Curr Treat Options Neurol. 2017 Jan;19(1):3. doi: 10.1007/s11940-017-0439-4.
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Febrile infection-related epilepsy syndrome treated with anakinra.用阿那白滞素治疗发热感染相关癫痫综合征。
Ann Neurol. 2016 Dec;80(6):939-945. doi: 10.1002/ana.24806. Epub 2016 Nov 14.
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Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial.白细胞介素-1受体阻断与具有巨噬细胞活化综合征特征的脓毒症患者死亡率降低相关：对一项既往III期试验的重新分析
Crit Care Med. 2016 Feb;44(2):275-81. doi: 10.1097/CCM.0000000000001402.
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J Cereb Blood Flow Metab. 2011 Feb;31(2):439-47. doi: 10.1038/jcbfm.2010.103. Epub 2010 Jul 14.
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