Department of Inorganic and Analytical Chemistry, University of Geneva, Quai Ernest-Ansermet 30, CH-1211 Geneva, Switzerland.
BioImaging Center, Department of Biochemistry, University of Geneva, Quai Ernest-Ansermet 30, CH-1211 Geneva, Switzerland.
Anal Chem. 2020 Nov 3;92(21):14319-14324. doi: 10.1021/acs.analchem.0c02920. Epub 2020 Oct 21.
Ion-selective electrodes (ISEs) are widely used analytical devices to selectively measure ionic species. Despite significant advances in recent years, ion-selective membranes are still mostly prepared in the same manner, by preloading the selective components into a solvent that is subsequently cast into a membrane or film. This paper describes an alternative method to prepare ISE membranes by mass transfer of the sensing components from an emulsion phase. Specifically, blank (undoped) plasticized poly(vinyl chloride) (PVC) membranes mounted into an electrode body are immersed into an aqueous solution containing analyte ions and an appropriate emulsion of the desired sensing components to allow their transfer into the membrane. The concept is demonstrated with conventional membrane electrodes containing an inner solution as well as all-solid-state electrodes. It is shown to be universally useful for the realization of ISEs for K, Na, Ca, and NO.
离子选择性电极（ISE）是广泛用于选择性测量离子种类的分析仪器。尽管近年来取得了重大进展，但离子选择性膜仍然大多以相同的方式制备，即将选择性成分预加载到溶剂中，然后将其铸造成膜或薄膜。本文描述了一种通过从乳液相中传质来制备 ISE 膜的替代方法。具体来说，将装入电极体的空白（未掺杂）增塑聚氯乙烯（PVC）膜浸入含有分析物离子和所需传感成分的适当乳液的水溶液中，以允许它们转移到膜中。该概念通过含有内溶液的常规膜电极以及全固态电极得到了验证。结果表明，该方法对 K、Na、Ca 和 NO 等 ISE 的实现具有普遍的适用性。
