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规范先天性心脏病患儿心导管检查中的辐射暴露:来自巴西多中心注册研究的数据。

Standardizing Radiation Exposure during Cardiac Catheterization in Children with Congenital Heart Disease: Data from a Multicenter Brazilian Registry.

机构信息

Instituto de Cardiologia / Fundação Universitária de Cardiologia (IC/FUC),Porto Alegre, RS - Brasil.

Hospital do Coração, São Paulo, SP - Brasil.

出版信息

Arq Bras Cardiol. 2020 Dec;115(6):1154-1161. doi: 10.36660/abc.20190012.

Abstract

BACKGROUND

In recent years the increasing number of interventional procedures has resulted in growing concerns regarding radiation exposure for patients and staff. The evaluation of radiation exposure in children is difficult due to the great variability in body weight. Therefore, reference levels of radiation are not well defined for this population.

OBJECTIVES

To study and validate the ratio of dose-area product (DAP) to patient weight as a reference measurement of radiation for hemodynamic congenital heart disease procedures in children.

METHODS

This observational multicenter study uses data obtained from a Brazilian registry of cardiac catheterization for congenital heart disease from March 2013 to June 2014. Inclusion criteria were all patients aged <18 years old undergoing hemodynamic procedures for congenital heart disease, with recorded DAP doses. P-value < 0.05 was considered as statistically significant.

RESULTS

This study evaluated 429 patients with median age and weight of 50 (10, 103) months and 15 (7, 28) kg, respectively. Median DAP was 742.2 (288.8, 1,791.5) μGy.m2. There was a good correlation between DAP and weight-fluoroscopic time product(rs=0.66). No statistically significant difference was observed in DAP/weight ratio between therapeutic and diagnostic procedures. There was a wide variation in the DAP/weight ratio among the therapeutic procedures (p<0.001).

CONCLUSIONS

The DAP/weight ratio is the simplest and most applicable measurement to evaluate radiation exposure in a pediatric population. Although there is limited literature available, the doses obtained in the present study were similar to those previously found. Ongoing research is important to evaluate the impact of strategies to reduce radiation exposure in this population (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0).

摘要

背景

近年来,介入治疗的数量不断增加,人们越来越关注患者和医护人员的辐射暴露问题。由于儿童体重变化较大,因此评估儿童的辐射暴露情况较为困难。因此,该人群的辐射参考水平尚未明确界定。

目的

研究并验证剂量面积乘积(DAP)与患者体重的比值作为儿童先天性心脏病血流动力学介入治疗的辐射参考测量值。

方法

本观察性多中心研究使用了 2013 年 3 月至 2014 年 6 月巴西先天性心脏病心导管插入术登记处获取的数据。纳入标准为所有年龄<18 岁、接受先天性心脏病血流动力学介入治疗、有记录的 DAP 剂量的患者。P 值<0.05 被认为具有统计学意义。

结果

本研究共评估了 429 例患者,中位年龄和体重分别为 50(10,103)个月和 15(7,28)kg。中位 DAP 为 742.2(288.8,1791.5)μGy·m2。DAP 与透视时间-体重乘积(weight-fluoroscopic time product)之间存在良好的相关性(rs=0.66)。治疗性和诊断性介入程序之间 DAP/体重比值无统计学差异。治疗性介入程序中 DAP/体重比值差异较大(p<0.001)。

结论

DAP/体重比值是评估儿科人群辐射暴露最简单、最适用的测量方法。尽管现有文献有限,但本研究获得的剂量与之前的研究结果相似。开展相关研究对于评估减少该人群辐射暴露的策略的影响非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b59/8133734/db7a2655719b/0066-782X-abc-115-06-1154-gf01.jpg

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