Department of Ophthalmology, Humberto Castro Lima Hospital, Salvador, BA, Brasil.
Department of Ophthalmology, Centro Brasileiro de Cirurgia de Olhos, Goiânia, GO, Brasil.
Arq Bras Oftalmol. 2020 Sep-Oct;83(5):361-365. doi: 10.5935/0004-2749.20200044.
This study aims to compare the anatomical success rates of vitrectomy and SF6 gas tamponade for macular hole surgery with and without postoperative face-down posturing.
This was an observational, longitudinal, and retrospective case series analysis. The study included 52 eyes from 52 patients who underwent pars plana vitrectomy with trypan blue-assisted internal limiting membrane peeling and 25% SF6 tamponade for stages 2, 3, and 4 macular holes. After surgery, all patients were provided with a postoperative postural regimen: 31 patients were instructed not to maintain face-down posturing, whereas 21 were instructed to maintain face-down posturing for 7 days. The primary outcome measure was the macular hole closure rate. Statistical analysis was performed using Epi Info 7.1.
A total of 47 (90.3%) patients achieved hole closure. The nonface-down posturing group and face-down posturing group obtained closure rates of 90.3% and 90.4%, respectively; these rates were not significantly different. Statistical analysis revealed that no significant differences existed in sex, age, hole duration, hole stage, preoperative visual acuity, or postoperative visual acuity between the two groups.
Our results suggest that macular hole surgery with the use of short duration gas (SF6) is safe and effective and that maintaining a postural orientation of nonface-down posturing is also safe. However, these recommendations should be assessed further in a prospective and randomized study to comprehensively delineate the associated benefits and risks.
本研究旨在比较黄斑裂孔手术中玻璃体切除联合 SF6 气体填充与不联合术后面朝下体位治疗的解剖学成功率。
这是一项观察性、纵向、回顾性病例系列分析。研究纳入了 52 例 52 只眼,这些眼均接受了经睫状体平坦部玻璃体切除术联合曲安奈德辅助内界膜剥除术和 25%SF6 气体填充治疗 2、3 和 4 期黄斑裂孔。手术后,所有患者均接受了术后体位方案:31 例患者未被要求保持面朝下体位,21 例患者被要求保持面朝下体位 7 天。主要结局指标为黄斑裂孔闭合率。统计分析使用 Epi Info 7.1 进行。
共有 47(90.3%)例患者实现了裂孔闭合。非面朝下体位组和面朝下体位组的闭合率分别为 90.3%和 90.4%,差异无统计学意义。统计分析显示,两组间在性别、年龄、裂孔持续时间、裂孔分期、术前视力或术后视力方面无显著差异。
我们的结果表明,使用短时间气体(SF6)的黄斑裂孔手术是安全有效的,保持非面朝下体位也是安全的。然而,这些建议应该在一项前瞻性和随机研究中进一步评估,以全面描绘相关的益处和风险。