Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, PO Box 12000, Jerusalem, Ein Kerem, Israel.
Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem, Ein Kerem, Israel.
Int Urogynecol J. 2021 Jun;32(6):1513-1518. doi: 10.1007/s00192-020-04563-3. Epub 2020 Oct 21.
The objective was to compare clinical and anatomical outcomes between laparoscopic uterosacral ligament suspension (LUSLS) and vaginal colposuspension using the Uphold Lite™ mesh system for the treatment of apical prolapse.
We performed a comparative, retrospective cohort study. All women who underwent either vaginal colposuspension with the Uphold Lite™ System or LUSLS for treatment of apical prolapse between 2010 and 2019 were included. The groups were compared with regard to demographic, pre-operative, intra-operative, and post-operative data. Outcome measures included clinical and anatomical cure, as well as a composite outcome. The PGI-I questionnaire was used to determine patient satisfaction.
One-hundred and nineteen women met the inclusion criteria, including 70 women who underwent LUSLS and 49 women who underwent vaginal colposuspension with the Uphold Lite™ mesh system. At a mean follow-up of 31.7 (SD = 18.1) months, the clinical cure rate was high for both groups, reaching 98.6% in the LUSLS group compared with 89.8% in the Uphold group (NS). Anatomical cure rate was 83.6% in the LUSLS group compared with 69.7% for the Uphold group (NS). With regard to the composite outcome, no difference was found, although a trend towards a higher success rate was noted in the LUSLS group (83.6% vs 66.7%, p = 0.055). Patient satisfaction measured using the PGI-I questionnaire was high, at 98.6% in the LUSLS group and 87.8% in the Uphold group (NS).
Laparoscopic uterosacral ligament suspension and vaginal colposuspension using the Uphold Lite™ mesh system both have high clinical cure rates.
目的是比较腹腔镜子宫骶骨韧带悬吊术（LUSLS）和阴道耻骨后悬吊术（VCS）治疗子宫顶端脱垂的临床和解剖学结果，所用的植入物是 Uphold Lite™网片系统。
我们进行了一项对比性、回顾性队列研究。纳入了 2010 年至 2019 年期间采用 Uphold Lite™系统行阴道耻骨后悬吊术或 LUSLS 治疗子宫顶端脱垂的所有女性。比较了两组患者的人口统计学、术前、术中及术后资料。观察指标包括临床和解剖学治愈情况以及复合结局。采用 PGIS 问卷评估患者满意度。
119 名女性符合纳入标准，其中 70 例行 LUSLS，49 例行阴道耻骨后悬吊术。平均随访 31.7（SD=18.1）个月，两组患者的临床治愈率均较高，LUSLS 组为 98.6%，Uphold 组为 89.8%（NS）。LUSLS 组的解剖学治愈率为 83.6%，Uphold 组为 69.7%（NS）。在复合结局方面，两组间无差异，但 LUSLS 组的成功率有升高趋势（83.6% vs 66.7%，p=0.055）。PGIS 问卷评估的患者满意度高，LUSLS 组为 98.6%，Uphold 组为 87.8%（NS）。
腹腔镜子宫骶骨韧带悬吊术和阴道耻骨后悬吊术（Uphold Lite™网片系统）均具有较高的临床治愈率。
