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闭目难立试验

Romberg Test

作者信息

Forbes Kaprive Jessica, Munakomi Sunil, Cronovich Heather A.

机构信息

Kathmandu University

Henry Ford Macomb

PMID:33085334
Abstract

The Romberg's sign or Romberg's test is named after a European neurologist, Mortiz Romberg; historically, this was described by Marshall Hall, Moritz Romberg, and Bernardus Brach. Initially, this sign was tethered specifically with tertiary syphilis patients who exhibited neurologic signs of late-stage disease referred to as locomotor ataxia or tabes dorsalis. When examining a patient's neurological effects from sequelae involving late-stage syphilis, the Romberg sign became a precise test to determine the integrity of the dorsal column pathway of the brain and spinal cord, which controls proprioception. Proprioception is the sense of awareness of the position and movement of the body. Romberg described this sign as a severe postural impairment in a darkroom setting or with eyes closed of patients with severe damage to the posterior dorsal columns of the spinal cord. Used as a precise clinical tool, the Romberg test is positive if a patient cannot maintain an upright stance with vision eliminated or in the darkness.  Often the Romberg test can be confused as a sign of cerebellar disease, but this test demonstrates the effects of posterior column disease. Normal stance in a person is governed by the integrity of vision, proprioception, and vestibular function. The ability to gauge actual proprioception status can be confounded by the vestibular and vision somatosensory system, which may compensate for vestibular function and vision. The Romberg sign removes the visual and vestibular components that contribute to maintaining balance and can thus identify a proprioception-related neurologic disease.  The Romberg sign is said to be positive in a patient who can stand with his feet placed together and eyes open but paradoxically sways or falls while closing his eyes, thereby eliminating his visual cues.

摘要

闭目难立征或罗姆伯格试验是以欧洲神经学家莫里茨·罗姆伯格的名字命名的;历史上,马歇尔·霍尔、莫里茨·罗姆伯格和贝尔纳德斯·布拉赫都曾对此进行过描述。最初,这个体征特别与三期梅毒患者相关,这些患者表现出晚期疾病的神经体征,即运动性共济失调或脊髓痨。在检查梅毒晚期后遗症对患者神经系统的影响时,闭目难立征成为确定大脑和脊髓背柱通路完整性的精确测试,该通路控制本体感觉。本体感觉是对身体位置和运动的感知意识。罗姆伯格将这个体征描述为在暗室环境中或闭眼时,脊髓后柱严重受损患者出现的严重姿势障碍。作为一种精确的临床工具,如果患者在视觉消除或处于黑暗中时无法保持直立姿势,闭目难立试验即为阳性。通常,闭目难立试验可能会被误诊为小脑疾病的体征,但该试验显示的是后柱疾病的影响。人的正常姿势受视觉、本体感觉和前庭功能完整性的支配。评估实际本体感觉状态的能力可能会受到前庭和视觉体感系统的干扰,这两个系统可能会代偿前庭功能和视觉。闭目难立征消除了有助于维持平衡的视觉和前庭成分,因此可以识别与本体感觉相关的神经系统疾病。据说,如果患者双脚并拢站立、眼睛睁开时能够站立,但闭上眼睛时却反常地摇晃或跌倒,从而消除了视觉线索,那么该患者的闭目难立征即为阳性。

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Romberg Test闭目难立试验
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Romberg's sign: development, adoption, and adaptation in the 19th century.闭目难立征:19世纪的发展、应用与适应
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The Romberg sign and early instruments for measuring postural sway.闭目难立征及早期姿势摆动测量仪器
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Moritz Heinrich Romberg (1795-1873): Early founder of neurology.莫里茨·海因里希·罗默(1795-1873):神经病学的早期奠基人。
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Romberg's test revisited: Changes in classical and advanced sway metrics in patients with pure sensory neuropathy.重新审视 Romberg 试验:纯感觉神经病患者经典和先进摆动测量的变化。
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Relationship between postural stability and spatial hearing.姿势稳定性与空间听觉之间的关系。
J Am Acad Audiol. 2013 Oct;24(9):782-8. doi: 10.3766/jaaa.24.9.3.
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Vestibular contributions to the Romberg test: Testing semicircular canal and otolith function.前庭对罗姆伯格试验的影响:检测半规管和耳石功能。
Eur J Neurol. 2021 Sep;28(9):3211-3219. doi: 10.1111/ene.14942. Epub 2021 Jun 23.
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Romberg and his sign.罗姆伯格及其征
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Does walking change the Romberg sign?步行会改变闭目难立征吗?
Eur Spine J. 2009 Oct;18(10):1528-31. doi: 10.1007/s00586-009-1008-7. Epub 2009 Apr 22.
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Nineteenth-century contributions to the mechanical recording of postural sway.19世纪对姿势摇摆的机械记录所做的贡献。
Arch Neurol. 2001 Jul;58(7):1147-50. doi: 10.1001/archneur.58.7.1147.