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68Ga-PSMA-11 和 18F-Fluciclovine PET/CT 中的少突胶质细胞瘤。

Oligodendroglioma in 68Ga-PSMA-11 and 18F-Fluciclovine PET/CT.

机构信息

From the Divisions of Nuclear Medicine.

General Radiology, Department of Radiology, Medical University of Graz, Graz, Austria.

出版信息

Clin Nucl Med. 2021 Apr 1;46(4):e231-e232. doi: 10.1097/RLU.0000000000003347.

Abstract

Prostate cancer (PC) is one of the most common cancers affecting men worldwide, with a high recurrence rate after therapy. 68Ga-PSMA-11 and 18F-fluciclovine are PET imaging tracers for the detection of recurrence sites in PC patients. 68Ga-PSMA-11 is a membrane antigen overexpressed by tumor cells, whereas 18F-fluciclovine targets increased amino acid transporter in the membrane of cancer cells. We report a case of an 83-year-old man with known oligodendroglioma and biochemically recurrent PC who shows a high focal 68Ga-PSMA-11 and 18F-fluciclovine uptake in the brain.

摘要

前列腺癌(PC)是全球男性最常见的癌症之一,治疗后复发率很高。68Ga-PSMA-11 和 18F-氟柳氯胺是用于检测 PC 患者复发部位的 PET 成像示踪剂。68Ga-PSMA-11 是肿瘤细胞过度表达的膜抗原,而 18F-氟柳氯胺则靶向癌细胞膜中增加的氨基酸转运体。我们报告了一例 83 岁已知患有少突神经胶质瘤和生化复发前列腺癌的男性,其大脑中显示出高焦点 68Ga-PSMA-11 和 18F-氟柳氯胺摄取。

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