Takizawa Hiroki, Abe Kouichi, Ueki Teiichirou
Department of Urology, Hadano Red Cross Hospital.
Nihon Hinyokika Gakkai Zasshi. 2019;110(4):261-265. doi: 10.5980/jpnjurol.110.261.
An 80-year-old man was referred to our hospital with a complaint of acute urinary retention due to hematuria. Cystoscopy revealed a broad-based tumor arising in a diverticulum on the right lateral wall of the bladder. Transurethral resection of the bladder tumor (TURBT) was performed immediately. The pathological diagnosis was small-cell carcinoma without any urothelial carcinomas, and clinical examination revealed a clinical stage of T3b, N0, M0. Thus, 3 courses of neoadjuvant chemotherapy with cisplatin and irinotecan were administered. Chemotherapy resulted in tumor shrinkage, and partial cystectomy was performed under a diagnosis of stage pT3aN0M0 bladder cancer in the diverticulum. The patient is alive without any evidence of tumor recurrence at 13 months after the operation. To our knowledge, this is the first case report in Japan of small-cell carcinoma in a diverticulum of the urinary bladder, for which partial cystectomy was performed after chemotherapy.
一名80岁男性因血尿伴急性尿潴留被转诊至我院。膀胱镜检查发现膀胱右侧壁憩室内有一基底较宽的肿瘤。随即进行了经尿道膀胱肿瘤切除术(TURBT)。病理诊断为小细胞癌,无任何尿路上皮癌成分,临床检查显示临床分期为T3b、N0、M0。因此,给予了3个疗程的顺铂和伊立替康新辅助化疗。化疗导致肿瘤缩小,在诊断为憩室内pT3aN0M0期膀胱癌后进行了部分膀胱切除术。患者术后13个月存活,无肿瘤复发迹象。据我们所知,这是日本首例膀胱憩室内小细胞癌经化疗后行部分膀胱切除术的病例报告。