Bork K
Hautklinik der Johannes Gutenberg-Universität Mainz.
Hautarzt. 1987 Jun;38(6):348-51.
The coexistence of psoriasis and bullous pemphigoid in 44 patients has been described in the literature. In the majority of cases no causative agent was found for the development of bullous pemphigoid, but in many cases the bullous eruption was related to antipsoriatic treatment such as PUVA, anthralin, tar and salicylic acid. A 46-year-old man with a 20-year history of psoriasis who developed bullous pemphigoid without any previous therapy is described. After clearing, a later exacerbation of both psoriasis and bullous pemphigoid indicated that there is a pathogenetic relationship between the diseases. Among 72 patients with bullous pemphigoid no others suffered from psoriasis.
文献中已描述了44例银屑病与大疱性类天疱疮共存的病例。在大多数病例中,未发现导致大疱性类天疱疮发生的病原体,但在许多病例中,水疱性皮疹与光化学疗法(PUVA)、蒽林、焦油和水杨酸等抗银屑病治疗有关。本文描述了一名有20年银屑病病史的46岁男性,在未接受任何先前治疗的情况下发生了大疱性类天疱疮。皮疹消退后,银屑病和大疱性类天疱疮随后的加重表明这两种疾病之间存在发病机制上的关联。在72例大疱性类天疱疮患者中,没有其他患者患有银屑病。