Department of Radiology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Abdom Radiol (NY). 2021 May;46(5):2203-2218. doi: 10.1007/s00261-020-02817-8. Epub 2020 Oct 22.
Ferumoxytol is an injectable ultrasmall superparamagnetic iron oxide that has been gaining interest regarding its off-label use as an intravenous contrast agent in magnetic resonance imaging (MRI). Due to its large particle size, its use with MRI produces exquisite images of blood vessels with little background contamination or parenchymal enhancement of the abdominopelvic organs, except for the liver and spleen. Because ferumoxytol is neither an iodinated nor a gadolinium-based contrast agent, there are no restrictions for its use in patients with poor renal function. This article will highlight normal features in ferumoxytol-enhanced MRI in the abdomen and pelvis as well as its applications in evaluating vascular pathology, presurgical planning, and other problem solving.
菲立磁是一种可注射的超顺磁性氧化铁纳米颗粒，因其作为磁共振成像（MRI）的静脉内造影剂的潜在应用而备受关注。由于其颗粒较大，在使用 MRI 时，除了肝脏和脾脏外，它可以产生对腹部和盆腔血管具有精细对比的图像，而背景污染或实质器官增强很小。由于菲立磁既不是碘基也不是钆基造影剂，因此肾功能不佳的患者使用它没有限制。本文将重点介绍腹部和盆腔菲立磁增强 MRI 的正常特征及其在评估血管病变、术前规划和其他问题解决方面的应用。
