Stevens James P, Brownell Jefferson N, Freeman A Jay, Bashaw Hillary
Children's Healthcare of Atlanta, Division of Gastroenterology, Hepatology and Nutrition Atlanta, GA.
Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia.
J Pediatr Gastroenterol Nutr. 2020 Nov;71(5):669-671. doi: 10.1097/MPG.0000000000002860.
In April 2020, a newly recognized pediatric disorder associated with COVID-19 characterized by significant inflammation with symptoms resembling Kawasaki disease was described by medical teams in the United States, the United Kingdom, and Italy. Before these reports, data from the initial COVID-19 outbreaks in China had not found the virus to cause significant morbidity or mortality in children. To date, pancreatitis has not yet been reported in either acute SARS-CoV-2 infection in children or the subsequent inflammatory syndrome. We describe a patient who presented with acute pancreatitis before rapidly progressing to multisystem organ dysfunction consistent with multisystem inflammatory syndrome in children due to COVID-19. Clinicians should be aware that in the context of the COVID-19 pandemic, pancreatitis can be an early presentation of multisystem inflammatory syndrome in children.
2020年4月，美国、英国和意大利的医疗团队描述了一种新发现的与新冠病毒疾病相关的儿科疾病，其特征为严重炎症，症状类似川崎病。在这些报告之前，中国首次出现新冠病毒疾病疫情的数据并未发现该病毒会导致儿童出现显著的发病率或死亡率。迄今为止，儿童急性感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）或随后的炎症综合征中均未报告胰腺炎。我们描述了一名患者，该患者在迅速发展为多系统器官功能障碍之前出现了急性胰腺炎，这种多系统器官功能障碍与儿童因新冠病毒疾病导致的多系统炎症综合征一致。临床医生应意识到，在新冠病毒疾病大流行的背景下，胰腺炎可能是儿童多系统炎症综合征的早期表现。
