Department of Neurosurgery, University Hospital Complex of Badajoz, Badajoz, Spain.
Department of Pathology, University Hospital Complex of Badajoz, Badajoz, Spain.
Br J Neurosurg. 2023 Oct;37(5):1223-1227. doi: 10.1080/02688697.2020.1837729. Epub 2020 Oct 23.
Meningiomas have a 5 year recurrence rate of 8%. Histological grade and extent of resection are the two main prognostic factors. Cystic meningiomas represent between 2 and 4% of meningiomas, and the complete resection rate in these cases is 62.7%. 5-ALA has been shown to be useful in detecting tumour remnants that could go unnoticed by the conventional microsurgical technique, thereby achieving more complete resections. We present the case of a 66-year-old patient with a frontal convexity meningioma, presenting with a cystic component and bone invasion, who was treated using 5-ALA fluorescence-guided surgery. Fluorescence emission from the tumour tissue allowed the areas of bone invasion and the cystic wall to be identified, achieving complete resection.
脑膜瘤的 5 年复发率为 8%。组织学分级和切除范围是两个主要的预后因素。囊性脑膜瘤占脑膜瘤的 2%至 4%，这些病例的完全切除率为 62.7%。5-ALA 已被证明可用于检测传统显微外科技术可能遗漏的肿瘤残余物，从而实现更完全的切除。我们报告了一例 66 岁患者，患有额凸脑膜瘤，表现为囊性成分和骨侵犯，使用 5-ALA 荧光引导手术进行治疗。肿瘤组织的荧光发射使骨侵犯和囊性壁的区域得以识别，从而实现了完全切除。
