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使用 AD823X 模拟前端微芯片和开源开发验证制造便携式 ECG 设备。

Fabricating a Portable ECG Device Using AD823X Analog Front-End Microchips and Open-Source Development Validation.

机构信息

Engineering Faculty, Autonomous University of Baja California, Blvd. Benito Juárez s/n, C.P. Mexicali 21280, B.C., Mexico.

Engineering Institute, Autonomous University of Baja California, Blvd. Benito Juárez s/n, C.P. Mexicali 21280, B.C., Mexico.

出版信息

Sensors (Basel). 2020 Oct 21;20(20):5962. doi: 10.3390/s20205962.

DOI:10.3390/s20205962
PMID:33096907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7589626/
Abstract

Relevant to mobile health, the design of a portable electrocardiograph (ECG) device using AD823X microchips as the analog front-end is presented. Starting with the evaluation board of the chip, open-source hardware and software components were integrated into a breadboard prototype. This required modifying the microchip with the breadboard-friendly Arduino Nano board in addition to a data logger and a Bluetooth breakout board. The digitized ECG signal can be transmitted by serial cable, via Bluetooth to a PC, or to an Android smartphone system for visualization. The data logging shield provides gigabytes of storage, as the signal is recorded to a microSD card adapter. A menu incorporates the device's several operating modes. Simulation and testing assessed the system stability and performance parameters in terms of not losing any sample data throughout the length of the recording and finding the maximum sampling frequency; and validation determined and resolved problems that arose in open-source development. Ultimately, a custom printed circuit board was produced requiring advanced manufacturing options of 2.5 mils trace widths for the small package components. The fabricated device did not degrade the AD823X noise performance, and an ECG waveform with negligible distortion was obtained. The maximum number of samples/second was 2380 Hz in serial cable transmission, whereas in microSD recording mode, a continuous ECG signal for up to 36 h at 500 Hz was verified. A low-cost, high-quality portable ECG for long-term monitoring prototype that reasonably complies with electrical safety regulations and medical equipment design was realized.

摘要

与移动健康相关，本研究提出了一种使用 AD823X 微芯片作为模拟前端的便携式心电图（ECG）设备设计。从芯片评估板开始，将开源硬件和软件组件集成到一个原型电路板中。这需要对微芯片进行修改，使其与面包板兼容的 Arduino Nano 板一起使用，此外还需要数据记录器和蓝牙分线板。数字化的 ECG 信号可以通过串口电缆、蓝牙传输到 PC，或者传输到 Android 智能手机系统进行可视化。数据记录器提供了数 GB 的存储空间，因为信号会被记录到 microSD 卡适配器中。菜单中包含设备的几种操作模式。通过仿真和测试，评估了系统的稳定性和性能参数，包括在记录过程中不丢失任何样本数据以及找到最大采样频率；并验证确定和解决了开源开发中出现的问题。最终，制作了一块定制的印刷电路板，需要先进的制造选项来满足小封装组件 2.5 密耳线宽的要求。所制作的设备没有降低 AD823X 的噪声性能，并且获得了具有可忽略失真的 ECG 波形。在串口电缆传输中，最大采样率为 2380 Hz，而在 microSD 记录模式下，验证了高达 36 小时、500 Hz 的连续 ECG 信号。实现了一种低成本、高质量的便携式长期监测原型心电图设备，该设备在电气安全法规和医疗设备设计方面具有合理性。

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