BengBu Medical College, Bengbu, Anhui, China; Department of Gastroenterology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China.
Department of Gastroenterology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China.
Gastroenterol Hepatol. 2021 Apr;44(4):286-292. doi: 10.1016/j.gastrohep.2020.08.003. Epub 2020 Oct 21.
The regular arrangement of collecting venules (RAC) refers to the appearance of multiple regular tiny veins in the body of the stomach and is considered to be very effective for identifying gastric mucosa with non-Helicobacter pylori infection. This meta-analysis was conducted to systematically evaluate the value of the sign in predicting a Helicobacter pylori-negative stomach and the relevant factors that may affect the performance of this prediction.
Two biomedical databases (PubMed and EMBASE) were systematically searched through April 20, 2020. The pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR) and area under the SROC curve (AUC) were calculated.
Fourteen articles with 4070 patients were included. The pooled sensitivity, specificity, PLR, NLR, DOR and AUC for the RAC in predicting non-Hp infection were 0.80 (0.67-0.89), 0.97 (0.93-0.98), 24.8 (12.2-50.8), 0.21 (0.12-0.36), 120 (47-301) and 0.97 (0.19-1.00), respectively.
The RAC is a valuable endoscopic feature for the prediction of patients without Hp infection.
胃小静脉规则排列（RAC）是指胃体部出现多条规则的细小静脉，被认为对识别非幽门螺杆菌感染的胃黏膜非常有效。本荟萃分析旨在系统评估该征象预测幽门螺杆菌阴性胃的价值，以及可能影响该预测性能的相关因素。
通过 2020 年 4 月 20 日系统检索了两个生物医学数据库（PubMed 和 EMBASE）。计算了 RAC 预测非幽门螺杆菌感染的汇总敏感性、特异性、阳性似然比（PLR）、阴性似然比（NLR）、诊断比值比（DOR）和 SROC 曲线下面积（AUC）。
纳入了 14 篇包含 4070 例患者的文章。RAC 预测非幽门螺杆菌感染的汇总敏感性、特异性、PLR、NLR、DOR 和 AUC 分别为 0.80（0.67-0.89）、0.97（0.93-0.98）、24.8（12.2-50.8）、0.21（0.12-0.36）、120（47-301）和 0.97（0.19-1.00）。
RAC 是预测无幽门螺杆菌感染患者的一种有价值的内镜特征。
