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对接受小儿肥胖症治疗的年轻成年人进行估计,发现接受减肥手术的人数比例较高。

High estimated prevalence of bariatric surgery in young adults treated for pediatric obesity.

机构信息

Department of Clinical Science, Intervention and Technology, Division of Pediatrics, Karolinska Institutet, Huddinge, Sweden; Allied Health Professionals Function, Occupational Therapy & Physiotherapy, Karolinska University Hospital, Stockholm, Sweden.

Department of Clinical Science, Intervention and Technology, Division of Pediatrics, Karolinska Institutet, Huddinge, Sweden.

出版信息

Surg Obes Relat Dis. 2021 Feb;17(2):398-405. doi: 10.1016/j.soard.2020.09.017. Epub 2020 Sep 16.

Abstract

BACKGROUND

Despite the modest effects of behavioral treatment on obesity in adolescence, bariatric surgery is rarely performed. Obesity often persists from childhood to adulthood, but it is not known how many individuals proceed with bariatric surgery in young adulthood.

OBJECTIVE

The aim of this study was to determine what proportion of individuals who received pediatric behavioral obesity treatment subsequently underwent bariatric surgery in early adulthood, and to identify predictors thereof.

SETTING

National registries, Sweden.

METHODS

In this prospective cohort study, the Swedish Childhood Obesity Treatment Register was linked to several national registers.

RESULTS

The childhood obesity cohort included 6502 (45% females) with a median age at follow-up of 21.7 years (interquartile range [IQR] 5.2). Of these, 8.2% underwent bariatric surgery at a median age of 20.9 years (IQR 4.2). The estimated cumulative incidence of bariatric surgery at age 30 was 21.5%. Obesity-related co-morbidities were identified in 31.7% before bariatric surgery in the childhood obesity cohort. Predictors of bariatric surgery were female sex, high body mass index standard deviation score (BMI SDS) at the start and end of treatment, poor treatment response, as well as own or parental cardiometabolic disease.

CONCLUSIONS

More than a fifth are estimated to undergo bariatric surgery in early adulthood, despite having received pediatric behavioral obesity treatment. Our results indicate that for many children, behavioral treatment is insufficient in reducing obesity and preventing obesity-related co-morbidity. Therefore, it is reasonable to assume that more effective treatment of adolescents with severe obesity, including more rigorous behavioral support and pharmacologic treatment, but also more frequent use of bariatric surgery, would benefit this group of patients.

摘要

背景

尽管行为治疗对青少年肥胖的效果有限,但很少进行减肥手术。肥胖常常从儿童期持续到成年期,但尚不清楚有多少人在成年早期会进行减肥手术。

目的

本研究旨在确定接受儿科行为性肥胖治疗的个体中有多少人随后在成年早期接受减肥手术,并确定其预测因素。

设置

国家登记处,瑞典。

方法

在这项前瞻性队列研究中,瑞典儿童肥胖治疗登记处与多个国家登记处进行了关联。

结果

儿童肥胖队列包括 6502 名(45%为女性)参与者,中位随访年龄为 21.7 岁(四分位间距 [IQR] 5.2)。其中,8.2%的人在 20.9 岁(IQR 4.2)时接受了减肥手术。30 岁时减肥手术的估计累积发生率为 21.5%。在儿童肥胖队列中,31.7%的人在减肥手术前存在肥胖相关合并症。减肥手术的预测因素为女性、治疗开始和结束时的身体质量指数标准差评分(BMI SDS)较高、治疗反应差,以及自身或父母的心血管代谢疾病。

结论

尽管接受了儿科行为性肥胖治疗,但估计有超过五分之一的人会在成年早期接受减肥手术。我们的研究结果表明,对于许多儿童来说,行为治疗不足以减少肥胖和预防肥胖相关合并症。因此,可以合理地假设,对严重肥胖的青少年进行更有效的治疗,包括更严格的行为支持和药物治疗,以及更频繁地使用减肥手术,将使这组患者受益。

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