IL-4 和 IL-13 在斑秃样表型中的潜在作用：临床视角。
A Potential Role for IL-4 and IL-13 in an Alopecia Areata-Like Phenotype: A Clinical Perspective.
机构信息
Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA; Department of Dermatology, Harvard Medical School, Boston, Massachusetts, USA.
出版信息
J Investig Dermatol Symp Proc. 2020 Nov;20(1):S58-S59. doi: 10.1016/j.jisp.2020.04.008.
Although alopecia areata (AA) has been traditionally classified as a strictly T helper type 1-mediated process, the T helper type 2 (Th2) pathway may contribute to an AA-like phenotype in some individuals. Herein, we describe three clinical cases that support the potential role of Th2 activity through the upregulation of IL-4 and IL-13 in an AA-like phenotype.
尽管斑秃（AA）传统上被归类为严格的 T 辅助细胞 1 型介导的过程，但 T 辅助细胞 2（Th2）途径可能在某些个体中导致类似 AA 的表型。在此，我们描述了三个临床病例，通过上调 IL-4 和 IL-13 支持 Th2 活性在类似 AA 的表型中的潜在作用。
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