European Advisory Board on Cat Diseases www.abcdcatsvets.org.
J Feline Med Surg. 2020 Nov;22(11):1084-1088. doi: 10.1177/1098612X20941787.
is a common obligate intracellular microsporidian parasite of rabbits that is increasingly recognised as a pathogen of cats and other mammalian species. These guidelines aim to review the literature on feline infection and provide recommendations on prevention and management.
infection should be considered as a differential diagnosis in cases of feline uveitis and cataract formation. It is not significantly associated with either chronic kidney disease or meningoencephalitis. E infection is more common in stray or feral cats than in pet cats.
Serological tests for antibody detection in the blood are easy to perform and can be useful for diagnosis, but their specificity is low as antibodies have been found in apparently healthy cats. PCR appears to be more sensitive than histopathology for diagnosis, and is more sensitive when performed on cataractous lenses compared with aqueous humour, although ease of sampling is an obvious limitation. Treatment is with fenbendazole for 3 weeks and phacoemulsification to remove microsporidia from cataractous lenses.
E is a potential zoonotic agent, and there is a particular risk to immunocompromised humans posed by infected rabbits. Albeit infrequent, spore shedding has been identified in cats, so care should be taken around infected cats.
是一种常见的兔源专性细胞内微孢子虫寄生虫，越来越多的证据表明它也是猫和其他哺乳动物的病原体。本指南旨在回顾有关猫感染的文献，并提供预防和管理的建议。
在猫葡萄膜炎和白内障形成的病例中，应考虑感染作为鉴别诊断。它与慢性肾病或脑膜脑炎并无显著相关性。与宠物猫相比，流浪猫或野外猫的感染更为常见。
血清学检测血液中的抗体检测容易进行，并且对诊断可能有用，但由于在明显健康的猫中也发现了抗体，因此特异性较低。PCR 似乎比组织病理学更敏感，与房水相比，在白内障晶状体上进行时更敏感，但取样的便利性是一个明显的限制。治疗方法是使用芬苯达唑治疗 3 周，并进行白内障超声乳化术以从白内障晶状体中去除微孢子虫。
是一种潜在的人畜共患病原体，受感染的兔子对免疫功能低下的人类构成特殊风险。虽然很少见，但已经在猫中发现了孢子脱落，因此应注意感染猫。
