Neuber Claudia, Koch Ulrike, Nell Barbara
Tierärztliches Gesundheitszentrum Oerzen, Melbeck, Deutschland.
Department für Kleintiere und Pferde, Veterinärmedizinische Universität Wien, Österreich.
Tierarztl Prax Ausg K Kleintiere Heimtiere. 2023 Feb;51(1):42-47. doi: 10.1055/a-1982-3564. Epub 2023 Mar 14.
A 2-year-old female mixed-breed canine patient from Namibia presented originally with chronic uveitis. A serum antibody titer and a PCR test performed on the aqueous humor were positive for encephalitozoon cuniculi. The left eye showed an immature anterior focal cortical cataract in the periphery with suspected lens capsule rupture and signs of chronic uveitis. An incipient anterior focal cortical cataract was also perceivable in the patient's right eye. Despite local treatment as well as systemic administration of carprofen, prednisolone, and fenbendazol recurrent uveitis occurred. The patient then underwent bilateral extracapsular lensextraction via phacoemulsification. A PCR test of the lens material was positive for encephalitozoon cuniculi strain III. Recurring uveitis and secondary glaucoma 10 months post-op resulted in permanent blindness of the left eye. The patient then continued to receive local anti-inflammatory treatment. The last recheck examination of both eyes, 31 month post-op, revealed no signs of uveitis. This is the first case reported of a cataract in a canine patient caused by encephalitozoon cuniculi strain III.
一只来自纳米比亚的2岁雌性混血犬最初表现为慢性葡萄膜炎。对房水进行的血清抗体滴度检测和聚合酶链反应（PCR）检测显示，兔脑炎微孢子虫呈阳性。左眼周边出现未成熟的前部局灶性皮质性白内障，怀疑晶状体囊破裂并有慢性葡萄膜炎体征。右眼也可察觉到初期的前部局灶性皮质性白内障。尽管进行了局部治疗以及全身性给予卡洛芬、泼尼松龙和芬苯达唑，但葡萄膜炎仍反复发作。随后，该犬通过超声乳化术接受了双侧囊外晶状体摘除术。晶状体材料的PCR检测显示兔脑炎微孢子虫III型呈阳性。术后10个月，葡萄膜炎复发并继发青光眼，导致左眼永久性失明。该犬随后继续接受局部抗炎治疗。术后31个月的最后一次双眼复查未发现葡萄膜炎迹象。这是首例由兔脑炎微孢子虫III型引起的犬白内障病例报告。
