Hamandi Mohanad, Nwafor C Ikenna, Baxter Ronald, Shinn Kathryn, Wooley Jordan, Vasudevan Anupama, Harrington Katherine, Schaffer Justin, Moore David, DiMaio J Michael, Ryan William H, Brinkman William T
Cardiovascular Research, Baylor Scott & White Research Institute, Plano, Texas.
Department of Cardiothoracic Surgery, Baylor Scott & White-The Heart Hospital, Plano, Texas.
Proc (Bayl Univ Med Cent). 2020 Jun 22;33(4):524-528. doi: 10.1080/08998280.2020.1771163.
Bentall and valve-sparing root replacement (VSRR) procedures are established treatments for aortic root disease. We present a single-center retrospective analysis comparing outcomes of bioprosthetic Bentall (BB), mechanical Bentall (MB), and VSRR patients from November 2007 to October 2016. Survival analysis was performed to evaluate the composite endpoint of freedom from recurrent aortic insufficiency, reoperation, or death. Of the 170 patients, BB was performed in 36 patients, MB in 63 patients, and VSRR in 71 patients. For BB, MB, and VSRR, the mean age was 63.8, 45.5, and 49.2 years ( < 0.001), respectively. Additionally, significantly more patients in the MB group (n = 32, 50.8%, < 0.001) than in the BB and VSRR groups had prior cardiac surgeries. Cardiopulmonary bypass time and cross-clamp time were significantly longer in the VSRR group ( = 0.04 and 0.0005, respectively). Despite the complexity of the procedure, VSRR patients had higher combined freedom from death and reoperation than patients in the BB or MB groups. Elective Bentall root replacement is an excellent option for patients with root disease. Patients undergoing Bentall tend to have more severe or emergent cases, making them unlikely candidates for VSRR. VSRR in experienced centers carries equivalent morbidity and mortality and improved survival.
Bentall手术和保留瓣膜的主动脉根部置换术(VSRR)是治疗主动脉根部疾病的既定方法。我们进行了一项单中心回顾性分析,比较了2007年11月至2016年10月期间接受生物瓣Bentall手术(BB)、机械瓣Bentall手术(MB)和VSRR的患者的结局。进行生存分析以评估无复发性主动脉瓣关闭不全、再次手术或死亡的复合终点。170例患者中,36例行BB手术,63例行MB手术,71例行VSRR手术。BB组、MB组和VSRR组的平均年龄分别为63.8岁、45.5岁和49.2岁(<0.001)。此外,MB组中曾接受过心脏手术的患者(n = 32,50.8%,<0.001)明显多于BB组和VSRR组。VSRR组的体外循环时间和主动脉阻断时间明显更长(分别为P = 0.04和0.0005)。尽管手术复杂,但VSRR患者的死亡和再次手术联合自由度高于BB组或MB组患者。择期Bentall主动脉根部置换术是根部疾病患者的极佳选择。接受Bentall手术的患者往往病情更严重或更紧急,因此不太可能成为VSRR的候选者。在经验丰富的中心进行VSRR,其发病率和死亡率相当,且生存率有所提高。