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药剂师监督干预对新诊断糖尿病患者健康相关生活质量的影响评估:一项前后对照设计。

Impact assessment of pharmacist-supervised intervention on health-related quality of life of newly diagnosed diabetics: A pre-post design.

作者信息

Upadhyay Dinesh K, Mohamed Ibrahim Mohamed Izham, Mishra Pranaya, Alurkar Vijay M

机构信息

Faculty of Pharmacy, AIMST University, Semeling, Jalan Bedong, Kedah Darul Aman, Bedong, Kedah, Malaysia.

Department of Social and Administrative Pharmacy, College of Pharmacy, Qatar University, Doha, Qatar.

出版信息

J Pharm Bioallied Sci. 2020 Jul-Sep;12(3):234-245. doi: 10.4103/jpbs.JPBS_6_20. Epub 2020 Jul 18.

Abstract

INTRODUCTION

Diabetics face a series of challenges that affect all aspects of their daily life. Diabetes related complications adversely affect patient's health-related quality of life (HRQoL). Knowledge and self-care skills of diabetics are corner stones to improve their HRQoL.

OBJECTIVE

To assess the impact of pharmacist-supervised intervention on HRQoL of newly diagnosed diabetics using an Audit of Diabetes-Dependent Quality of Life (ADDQoL) questionnaire.

MATERIALS AND METHODS

A pre-post comparison study was conducted among the control group (CG), test 1 group (T1G) and test 2 group (T2G) patients with three treatment arms to explore the impact of pharmacist-supervised intervention on HRQoL of newly diagnosed diabetics for 18 months. Patients' HRQoL scores were determined using ADDQoL questionnaire at baseline, 3, 6, 9 and 12-months. T1G patients received pharmacist's intervention whereas T2G patients received diabetic kit demonstration in addition to pharmacist's intervention. CG patients were deprived of pharmacist intervention and diabetic kit demonstration, and only received care from attending physician/nurses. Non-parametric tests were used to find the differences in an average weighted impact scores (AWIS) among the groups before and after the intervention at ≤ 0.05.

RESULTS

Friedman test identified significant ( < 0.001) improvement in AWIS among the test groups' patients. Differences in scores were significant between T1G and T2G at 6-months ( = 0.033), 9-months ( < 0.001) and 12-months ( < 0.001); between CG and T1G at 12-months ( < 0.001) and between CG and T2G at 9-months ( < 0.001) and 12-months ( < 0.0010) on Mann.Whitney U test.

CONCLUSION

Pharmacist's intervention improved AWIS of test groups' diabetics. Diabetic kit demonstration strengthened the disease understanding and selfcare skills of T2G patients. Disease and self-care awareness among diabetics should be increased in Nepali healthcare system by involving pharmacists for better patient's related outcomes.

摘要

引言

糖尿病患者面临一系列影响其日常生活各方面的挑战。糖尿病相关并发症会对患者的健康相关生活质量(HRQoL)产生不利影响。糖尿病患者的知识和自我护理技能是改善其HRQoL的基石。

目的

使用糖尿病相关生活质量评估(ADDQoL)问卷评估药剂师监督干预对新诊断糖尿病患者HRQoL的影响。

材料与方法

在对照组(CG)、试验1组(T1G)和试验2组(T2G)患者中进行了一项前后比较研究,该研究有三个治疗组,以探讨药剂师监督干预对新诊断糖尿病患者HRQoL的影响,为期18个月。在基线、3个月、6个月、9个月和12个月时,使用ADDQoL问卷确定患者的HRQoL评分。T1G组患者接受药剂师干预,而T2G组患者除接受药剂师干预外,还接受糖尿病工具演示。CG组患者未接受药剂师干预和糖尿病工具演示,仅接受主治医生/护士的护理。使用非参数检验来发现干预前后各小组之间平均加权影响得分(AWIS)的差异,显著性水平为≤0.05。

结果

弗里德曼检验确定试验组患者的AWIS有显著改善(<0.001)。在6个月(=0.033)、9个月(<0.001)和12个月时,T1G组和T2G组之间的得分差异显著;在12个月时,CG组和T1G组之间差异显著(<0.001),在9个月(<0.001)和12个月(<0.0010)时,CG组和T2G组之间差异显著(曼-惠特尼U检验)。

结论

药剂师的干预改善了试验组糖尿病患者的AWIS。糖尿病工具演示增强了T2G组患者对疾病的理解和自我护理技能。在尼泊尔医疗保健系统中,应通过让药剂师参与来提高糖尿病患者的疾病和自我护理意识,以获得更好的患者相关结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8c9/7574756/ed31961a85ec/JPBS-12-234-g002.jpg

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