Editorial: From Peptide and Protein Toxins to Ion Channel Structure/Function and Drug Design.
作者信息
Nicke Annette, Ulens Chris, Rolland Jean-Francois, Tsetlin Victor I
机构信息
Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Laboratory of Structural Neurobiology, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
出版信息
Front Pharmacol. 2020 Sep 25;11:548366. doi: 10.3389/fphar.2020.548366. eCollection 2020.
Abstract
摘要
相似文献
1
Editorial: From Peptide and Protein Toxins to Ion Channel Structure/Function and Drug Design.社论：从肽和蛋白质毒素到离子通道结构/功能与药物设计
Front Pharmacol. 2020 Sep 25;11:548366. doi: 10.3389/fphar.2020.548366. eCollection 2020.
2
Polypeptide and peptide toxins, magnifying lenses for binding sites in nicotinic acetylcholine receptors.多肽和肽毒素，烟碱型乙酰胆碱受体结合位点的放大镜。
Biochem Pharmacol. 2009 Oct 1;78(7):720-31. doi: 10.1016/j.bcp.2009.05.032. Epub 2009 Jun 6.
3
muO conotoxins inhibit NaV channels by interfering with their voltage sensors in domain-2.μ-芋螺毒素通过干扰结构域2中的电压感受器来抑制钠通道。
Channels (Austin). 2007 Jul-Aug;1(4):253-62. doi: 10.4161/chan.4847. Epub 2007 Aug 7.
4
Ion channel toxins and therapeutics: from cone snail venoms to ciguatera.离子通道毒素与治疗药物：从芋螺毒液到雪卡毒素
Ther Drug Monit. 2000 Feb;22(1):61-4. doi: 10.1097/00007691-200002000-00013.
5
A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins.一种新型的Kv1.6通道和烟碱型乙酰胆碱受体亚型的芋螺毒素抑制剂定义了一个新的芋螺毒素超家族。
Biochemistry. 2006 Jul 11;45(27):8331-40. doi: 10.1021/bi060263r.
6
Conotoxin modulation of voltage-gated sodium channels.芋螺毒素对电压门控钠通道的调节作用。
Int J Biochem Cell Biol. 2008;40(11):2363-8. doi: 10.1016/j.biocel.2007.08.017. Epub 2007 Sep 14.
7
Computational Structural Pharmacology and Toxicology of Voltage-Gated Sodium Channels.电压门控钠离子通道的计算结构药理学和毒理学。
Curr Top Membr. 2016;78:117-44. doi: 10.1016/bs.ctm.2015.12.001. Epub 2016 Mar 14.
8
A Transcriptomic Survey of Ion Channel-Based Conotoxins in the Chinese Tubular Cone Snail (Conus betulinus).中国筒锥螺（Conus betulinus）中基于离子通道的芋螺毒素的转录组学研究。
Mar Drugs. 2017 Jul 18;15(7):228. doi: 10.3390/md15070228.
9
Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABA(B) Receptor Activation Reveal a Minimal Functional Motif.通过GABA(B)受体激活抑制高电压激活钙通道的富含半胱氨酸α-芋螺毒素的构效关系研究揭示了一个最小功能基序。
Angew Chem Int Ed Engl. 2016 Apr 4;55(15):4692-6. doi: 10.1002/anie.201600297. Epub 2016 Mar 7.
10
A review on conotoxins targeting ion channels and acetylcholine receptors of the vertebrate neuromuscular junction.关于靶向脊椎动物神经肌肉接头离子通道和乙酰胆碱受体的芋螺毒素的综述。
Acta Physiol Pharmacol Ther Latinoam. 1999;49(4):257-67.
引用本文的文献
1
A 4/8 Subtype α-Conotoxin Vt1.27 Inhibits N-Type Calcium Channels With Potent Anti-Allodynic Effect.一种4/8亚型α-芋螺毒素Vt1.27可抑制N型钙通道并具有强效抗痛觉过敏作用。
Front Pharmacol. 2022 Apr 29;13:881732. doi: 10.3389/fphar.2022.881732. eCollection 2022.
2
Venom Peptide Toxins Targeting the Outer Pore Region of Transient Receptor Potential Vanilloid 1 in Pain: Implications for Analgesic Drug Development.靶向瞬时受体电位香草酸 1 外孔区的毒液肽毒素在疼痛中的作用：对镇痛药物开发的影响。
Int J Mol Sci. 2022 May 21;23(10):5772. doi: 10.3390/ijms23105772.
本文引用的文献
1
Nicotinic acetylcholine receptor inhibitors derived from snake and snail venoms.源自蛇和蜗牛毒液的烟碱型乙酰胆碱受体抑制剂。
Neuropharmacology. 2017 Dec;127:196-223. doi: 10.1016/j.neuropharm.2017.06.011. Epub 2017 Jun 13.
Zotero 插件