Kesserwani Hassan
Neurology, Flowers Medical Group, Dothan, USA.
Cureus. 2020 Sep 20;12(9):e10548. doi: 10.7759/cureus.10548.
With the ubiquity of susceptibility weighted imaging (SWI), cerebral microbleeds (CMBs) are fast becoming a prevalent phenomenon. They are tightly associated with age, neurodegeneration and diverse vascular etiologies. CMBs have a unique radiological signature. Their morphology, number and topology are quite informative. They also pose a therapeutic conundrum, as they are associated with the risk of cerebral hemorrhage. We present the case of an 86-year-old woman who has a vascular dementia, Binswanger's syndrome, and coronary artery disease, who presented with more than five CMBs. We present this case in order to highlight the dilemma of anti-platelet therapy in this group of patients and we demonstrate the cardinal radiologic features of CMBs. We then segue into the pathologic correlates of CMBs and associated risk factors. We finally analyze the risk of anti-platelet therapy in the presence of CMBs, and we unfold the latest data on CMB number and anti-platelet therapy.
随着磁敏感加权成像(SWI)的广泛应用,脑微出血(CMBs)正迅速成为一种普遍现象。它们与年龄、神经退行性变和多种血管病因密切相关。CMBs具有独特的影像学特征。其形态、数量和拓扑结构具有重要的信息价值。它们还带来了治疗难题,因为它们与脑出血风险相关。我们报告了一例86岁女性患者,她患有血管性痴呆、宾斯旺格综合征和冠状动脉疾病,出现了5个以上的CMBs。我们展示这个病例是为了突出该组患者抗血小板治疗的困境,并展示CMBs的主要影像学特征。然后我们转入CMBs的病理相关性及相关危险因素。我们最后分析了存在CMBs时抗血小板治疗的风险,并阐述了关于CMB数量和抗血小板治疗的最新数据。