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一例酷似血管炎的创伤性动脉血栓形成病例。

A Case of Trauma-Induced Arterial Thrombosis Mimicking Vasculitis.

作者信息

Kochar Tanureet, Bourji Khalil, Sarakbi Housam

机构信息

Sleep Medicine, Wayne State University Detroit Medical Center, Detroit, USA.

Rheumatology, Wayne State University Detroit Medical Center, Detroit, USA.

出版信息

Cureus. 2020 Sep 21;12(9):e10576. doi: 10.7759/cureus.10576.

DOI:10.7759/cureus.10576
PMID:33101820
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7577353/
Abstract

Vasculitis mimickers are structural or pathologic entities that resemble the vasculitis clinical presentation and/or diagnostic findings. Their presence can be a conundrum, and physicians require careful assessment and adequate knowledge physicians when considering a diagnosis of vasculitis. Although they are considered mimickers, the therapeutic approach for most of them differs widely from that of vasculitis as high-dose steroids and potent immunosuppressive regimens are usually indicated in the latter. In fact, steroid therapy is contraindicated and is considered harmful in some of these mimickers (e.g. segmental arterial mediolysis). Therefore, it is important to distinguish them from vasculitis to prevent complications from immunosuppressive therapy. Hereby, we present a challenging case of a 64-year-old man who presented with acute gangrenous changes on his right fingers due to arterial thrombus after trauma resembling vasculitis.

摘要

血管炎模仿者是指在临床表现和/或诊断结果上类似于血管炎的结构或病理实体。它们的存在可能是一个难题,医生在考虑血管炎诊断时需要仔细评估并具备足够的知识。尽管它们被视为模仿者,但大多数血管炎模仿者的治疗方法与血管炎有很大不同,因为后者通常需要大剂量类固醇和强效免疫抑制方案。事实上,类固醇治疗在某些血管炎模仿者中是禁忌的,甚至被认为是有害的(例如节段性动脉中层溶解)。因此,将它们与血管炎区分开来以防止免疫抑制治疗的并发症非常重要。在此,我们介绍一例具有挑战性的病例,一名64岁男性,因外伤后动脉血栓形成导致右手手指出现急性坏疽性改变,临床表现类似于血管炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac8b/7577353/d3ec47708dd9/cureus-0012-00000010576-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac8b/7577353/4985bde3757c/cureus-0012-00000010576-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac8b/7577353/39a1b6e8871a/cureus-0012-00000010576-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac8b/7577353/3d6e5cf88572/cureus-0012-00000010576-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac8b/7577353/d3ec47708dd9/cureus-0012-00000010576-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac8b/7577353/4985bde3757c/cureus-0012-00000010576-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac8b/7577353/39a1b6e8871a/cureus-0012-00000010576-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac8b/7577353/3d6e5cf88572/cureus-0012-00000010576-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac8b/7577353/d3ec47708dd9/cureus-0012-00000010576-i04.jpg

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本文引用的文献

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Int J Rheumatol. 2020 Feb 18;2020:8392542. doi: 10.1155/2020/8392542. eCollection 2020.
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Deep vein thrombosis and venous thromboembolism in trauma.创伤中的深静脉血栓形成和静脉血栓栓塞
Curr Opin Anaesthesiol. 2018 Apr;31(2):215-218. doi: 10.1097/ACO.0000000000000567.
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A Rare Case of Digital Ischemia and Gangrene in ANCA-Associated Vasculitis with Review of the Literature.ANCA相关性血管炎伴指端缺血和坏疽的罕见病例及文献复习
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Challenging mimickers of primary systemic vasculitis.
Rheum Dis Clin North Am. 2015;41(1):141-60, ix. doi: 10.1016/j.rdc.2014.09.011.
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Traumatic distal ulnar artery thrombosis.创伤性尺动脉远端血栓形成。
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Diagnostic approach to patients with suspected vasculitis.疑似血管炎患者的诊断方法。
Postgrad Med J. 2006 Aug;82(970):483-8. doi: 10.1136/pgmj.2005.042648.
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Hepatitis B virus-associated polyarteritis nodosa: clinical characteristics, outcome, and impact of treatment in 115 patients.乙型肝炎病毒相关性结节性多动脉炎:115例患者的临床特征、预后及治疗影响
Medicine (Baltimore). 2005 Sep;84(5):313-322. doi: 10.1097/01.md.0000180792.80212.5e.
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Hepatitis C virus, cryoglobulinaemia, and vasculitis: immune complex relations.丙型肝炎病毒、冷球蛋白血症与血管炎:免疫复合物的关系
Lancet Infect Dis. 2005 Apr;5(4):227-36. doi: 10.1016/S1473-3099(05)70053-0.
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Thromboembolism after trauma: an analysis of 1602 episodes from the American College of Surgeons National Trauma Data Bank.创伤后血栓栓塞:来自美国外科医师学会国家创伤数据库的1602例病例分析
Ann Surg. 2004 Sep;240(3):490-6; discussion 496-8. doi: 10.1097/01.sla.0000137138.40116.6c.