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Xp11.2易位性肾细胞癌的经皮射频消融:一例报告

Percutaneous radiofrequency ablation on a Xp11.2 Translocation Renal Cell Carcinoma: A case report.

作者信息

Kanas Alexandre Fligelman, Rovella Marcello Silveira, de Moura Mauricio Ruettimann Liberato, Leite Katia Ramos Moreira, Srougi Miguel, de Menezes Marcos Roberto

机构信息

Universidade de São Paulo, Department of Radiology, Interventional Radiology Group, Instituto de Radiologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil.

Instituto do Câncer do Estado de São Paulo, Brazil.

出版信息

Urol Case Rep. 2020 Sep 2;33:101401. doi: 10.1016/j.eucr.2020.101401. eCollection 2020 Nov.

DOI:10.1016/j.eucr.2020.101401
PMID:33102099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7574040/
Abstract

Xp11.2 Translocation Renal Cell Carcinoma is a very rare subtype of renal neoplasm. The present report describes the first confirmed reported case of percutaneous ablation of this subtype of tumor. The patient presented an aggressive local recurrence 12 months after the procedure, with an infiltrative large mass occupying almost the whole kidney. The patient was submitted to radical nephrectomy. As the use of ablative methods expands, the treatment of rare renal tumor subtypes, which can present unusual clinical outcomes, may become more frequent. It is essential that these uncommon outcomes are promptly recognized, allowing early therapeutic salvage approaches.

摘要

Xp11.2易位性肾细胞癌是一种非常罕见的肾肿瘤亚型。本报告描述了首例经证实的该亚型肿瘤经皮消融病例。患者在手术后12个月出现侵袭性局部复发,有一个浸润性大肿块几乎占据整个肾脏。患者接受了根治性肾切除术。随着消融方法的应用不断扩大,可能出现异常临床结果的罕见肾肿瘤亚型的治疗可能会更加频繁。及时识别这些不常见的结果并采取早期治疗挽救措施至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1504/7574040/ce1fc6b7ea5e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1504/7574040/622edc03986c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1504/7574040/b5395ae70fe4/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1504/7574040/ce1fc6b7ea5e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1504/7574040/622edc03986c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1504/7574040/b5395ae70fe4/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1504/7574040/ce1fc6b7ea5e/gr3.jpg

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本文引用的文献

1
Magnetic resonance imaging and computed tomography characteristics of renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion.与Xp11.2易位/TFE3基因融合相关的肾细胞癌的磁共振成像和计算机断层扫描特征
PLoS One. 2014 Jun 13;9(6):e99990. doi: 10.1371/journal.pone.0099990. eCollection 2014.
2
MiT translocation renal cell carcinomas: two subgroups of tumours with translocations involving 6p21 [t (6; 11)] and Xp11.2 [t (X;1 or X or 17)].MiT易位性肾细胞癌:两类肿瘤亚群,其易位涉及6p21 [t(6;11)]和Xp11.2 [t(X;1或X或17)] 。
Springerplus. 2014 May 13;3:245. doi: 10.1186/2193-1801-3-245. eCollection 2014.
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Ablative therapies for small renal tumours.
小肾肿瘤的消融治疗。
Nat Rev Urol. 2013 May;10(5):284-91. doi: 10.1038/nrurol.2013.68. Epub 2013 Apr 23.
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Xp11.2 translocation renal cell carcinoma.Xp11.2 易位性肾细胞癌。
Arch Pathol Lab Med. 2010 Jan;134(1):124-9. doi: 10.5858/2008-0391-RSR.1.
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Xp11.2 translocation renal cell carcinoma with very aggressive course in five adults.5例成人中具有侵袭性病程的Xp11.2易位性肾细胞癌
Am J Clin Pathol. 2007 Jul;128(1):70-9. doi: 10.1309/LR5G1VMXPY3G0CUK.