Klett Dane E, O'Neil Brock
Division of Urology, University of Utah School of Medicine and Huntsman Cancer Institute, Salt Lake City, Utah, USA.
J Endourol Case Rep. 2020 Sep 17;6(3):132-134. doi: 10.1089/cren.2019.0158. eCollection 2020.
Decidual reaction bladder endometriosis (DRBE) is exceedingly rare with few reported cases in the literature. It presents as a bladder mass during pregnancy, and may be accompanied by lower urinary tract symptoms. Histologic diagnosis is necessary to rule out primary bladder malignancy. We present a case of a bladder tumor identified during pregnancy. The mass was managed endoscopically and found to be DRBE, a rare benign entity. We present a 31 year old 15 weeks pregnant nonsmoker woman with a rapidly enlarging bladder mass concerning for primary bladder malignancy. Mass confirmed on formal renal/bladder ultrasound and in-office cystoscopy. After informed consent was obtained, the patient was taken to the operating room. A 5.5 cm bladder mass, with an atypical nodular appearance and minor calcifications, was identified. Transurethral resection of the mass was performed. Final pathology report showed florid endometriosis with stromal decidualization. Final diagnosis: pregnancy induced vesical decidualized endometriosis simulating a bladder tumor. Patient continued routine obstetrics follow-up, and has experienced no pregnancy-related complications. Three months after delivery the patient will follow up with outside urology provider for cystoscopy, and subsequent surgical management should it be necessary. DRBE is a rare benign bladder mass that presents in pregnancy. It can grow rapidly raising concern for an aggressive primary bladder malignancy. Any bladder mass identified in pregnancy should undergo early, appropriate work-up given the potential risk for bladder cancer. After diagnosis, DRBE is most often managed conservatively. After delivery, should the patient experience ongoing urinary symptoms, medical and surgical treatment options are available. Overall, DRBE is considered rare, but should be considered in the differential diagnosis for any bladder mass presenting during pregnancy.
蜕膜反应性膀胱子宫内膜异位症(DRBE)极为罕见,文献报道的病例很少。它在孕期表现为膀胱肿块,可能伴有下尿路症状。组织学诊断对于排除原发性膀胱恶性肿瘤很有必要。我们报告一例孕期发现的膀胱肿瘤病例。该肿块通过内镜处理,发现是DRBE,一种罕见的良性病变。我们介绍一位31岁、孕15周、不吸烟的女性,其膀胱肿块迅速增大,怀疑是原发性膀胱恶性肿瘤。肾脏/膀胱超声及门诊膀胱镜检查均证实有肿块。在获得知情同意后,患者被送往手术室。发现一个5.5厘米的膀胱肿块,外观呈非典型结节状且有少量钙化。对该肿块进行了经尿道切除术。最终病理报告显示为伴有间质蜕膜化的典型子宫内膜异位症。最终诊断:妊娠诱发的膀胱蜕膜化子宫内膜异位症,形似膀胱肿瘤。患者继续接受常规产科随访,未出现与妊娠相关的并发症。分娩后三个月,患者将到外院泌尿外科医生处进行膀胱镜检查,如有必要后续再进行手术治疗。DRBE是孕期出现的一种罕见的良性膀胱肿块。它可能迅速生长,引发对侵袭性原发性膀胱恶性肿瘤的担忧。鉴于存在膀胱癌的潜在风险,孕期发现的任何膀胱肿块都应尽早进行适当的检查。诊断后,DRBE通常采用保守治疗。分娩后,如果患者持续有泌尿系统症状,可采用药物和手术治疗方案。总体而言,DRBE虽被认为罕见,但对于孕期出现的任何膀胱肿块,在鉴别诊断时都应予以考虑。