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蛛网膜囊肿开窗术后癫痫和认知功能减退作为术后并发症:病例报告。

Epilepsy and cognitive deterioration as postoperative complications of the arachnoid cyst fenestration: Case report.

作者信息

Kwiatkowska Karolina, Milczarek Olga, Dębicka Magdalena, Baliga Zuzanna, Maryniak Agnieszka, Kwiatkowski Stanisław

机构信息

Jagiellonian University Medical College, Clinic of Children's Neurosurgery, Kraków, Poland.

Clinic of Neurosurgery and Neurotraumatology, The University Hospital, Kraków, Poland.

出版信息

Clin Neuropsychol. 2022 Aug;36(6):1599-1609. doi: 10.1080/13854046.2020.1837959. Epub 2020 Oct 26.

Abstract

With the aim of contributing to the discussion on treatment of patients with arachnoid cysts (AC) and their neuropsychological functioning, we present the case of a patient who has undergone surgery of AC located in the left Sylvian fissure. The patient had no cognitive deficits and no seizures before the cyst's fenestration. After the procedure, however, occurrences of seizures have been observed. Along with the concomitant epileptic seizures, aphasia and serious memory problems also developed. The initial pharmacological treatment of the seizures brought about unsatisfactory results. The treatment was therefore modified a number of times and ultimately, seizures were brought under control to some extent. Despite the varied efforts at neuropsychological rehabilitation, cognitive impairment was still persistent up to a year after the surgery. 1) While referring patients with AC for surgery, one should always consider both the positive outcomes and the unintended and deleterious consequences. A cyst fenestration could in some cases lead to epilepsy and cause neuropsychological symptoms such as anomic aphasia and cognitive deterioration with memory function impairment. 2) Neurological patients, especially the ones qualified for surgery, should always undergo neuropsychological examination. The lack of data from presurgical neuropsychological examination may impact further treatment of neurosurgical patients.

摘要

为了促进关于蛛网膜囊肿(AC)患者治疗及其神经心理功能的讨论,我们介绍一例位于左侧外侧裂的AC患者接受手术的病例。该患者在囊肿开窗术前无认知缺陷和癫痫发作。然而,手术后观察到癫痫发作。随着癫痫发作的同时,还出现了失语和严重的记忆问题。癫痫发作的初始药物治疗效果不理想。因此,治疗方案多次修改,最终癫痫发作在一定程度上得到了控制。尽管进行了多种神经心理康复努力,但术后长达一年仍存在认知障碍。1)在推荐AC患者进行手术时,应始终考虑积极结果以及意外和有害后果。囊肿开窗术在某些情况下可能导致癫痫,并引起神经心理症状,如命名性失语和伴有记忆功能损害的认知衰退。2)神经科患者,尤其是符合手术条件的患者,应始终接受神经心理检查。术前神经心理检查数据的缺乏可能会影响神经外科患者的进一步治疗。

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