在一名激素水平正常的隐匿性无精子症男性中发现的镶嵌型等臂Y染色体，其携带完整的无精子因子（AZF）区域。 - Suppr

Mosaic isodicentric Y chromosome harboring intact AZF region in a cryptozoospermic male with normal hormone levels.

作者信息

Xie Sheng-Yu, Tao Da-Chang, Yang Yuan

机构信息

Department of Medical Genetics, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China.

出版信息

Asian J Androl. 2021 Jul-Aug;23(4):437-438. doi: 10.4103/aja.aja_64_20.

DOI:10.4103/aja.aja_64_20

PMID:33106464

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8269828/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5ee/8269828/7cc643fc81a5/AJA-23-437-g001.jpg

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Mosaic isodicentric Y chromosome harboring intact AZF region in a cryptozoospermic male with normal hormone levels.在一名激素水平正常的隐匿性无精子症男性中发现的镶嵌型等臂Y染色体，其携带完整的无精子因子（AZF）区域。

Asian J Androl. 2021 Jul-Aug;23(4):437-438. doi: 10.4103/aja.aja_64_20.

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Andrologia. 2018 Mar;50(2). doi: 10.1111/and.12886. Epub 2017 Aug 24.

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J Assist Reprod Genet. 2013 Dec;30(12):1559-62. doi: 10.1007/s10815-013-0119-6. Epub 2013 Oct 25.

Non-chimerism and chimerism pseudo dicentric Y chromosome: two case reports about azoospermia and cytogenetic/molecular genetic analysis in the Chinese population.非嵌合体和嵌合体假二倍体 Y 染色体：两例中国人无精子症的病例报告及细胞遗传学/分子遗传学分析。

J Assist Reprod Genet. 2013 Apr;30(4):539-46. doi: 10.1007/s10815-013-9969-1. Epub 2013 Mar 16.

Isodicentric Y chromosomes and sex disorders as byproducts of homologous recombination that maintains palindromes.等臂双着丝粒Y染色体和性疾病是维持回文序列的同源重组的副产物。

Cell. 2009 Sep 4;138(5):855-69. doi: 10.1016/j.cell.2009.07.042.

Towards an understanding of the genetics of human male infertility: lessons from flies.

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Mosaic isodicentric Y chromosome harboring intact AZF region in a cryptozoospermic male with normal hormone levels.

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