Ziyaee Fateme, Alborzi Abdolvahab, Pouladfar Gholamreza, Pourabbas Bahman, Asaee Sadaf, Roosta Sareh
Department of Pediatrics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Arch Iran Med. 2020 Oct 1;23(10):665-671. doi: 10.34172/aim.2020.84.
The childhood period is considered to be the primary period for acquisition of the . The high prevalence rates from developing countries are associated with gastric cancer. A decreasing trend of its prevalence has been reported from different parts of the world. Determining the prevalence rate could be important in choosing preventive strategies. This study aimed to determine the prevalence of among a group of children from southern Iran to provide an update on the current status of the disease.
This is a cross-sectional population-based study conducted in Shiraz, southern Iran, from January 2014 to December 2015. Four groups including neonates, children aged 6 months to 3 years, 10- and 15-year-old children were included. Multi-monoclonal stool antibody test was used for diagnosis.
Among 436 participants, 24.8% (95% CI: 20.8-29.1) had a positive test for : 25% in neonates (95% CI: 16.2-36.1), 22% in children aged 6 months to 3 years (95% CI: 15.2-30.2), 19.5% in the 10-year-old (95% CI: 12.3-29.4), and 29.2% in 15-year-old children (95% CI: 21-39). Sex, age, number of siblings, owning a pet, parents' smoking status, parental education, residential area, birth weight, and feeding status were not found to be statistically significant predictors of antigen positivity ( > 0.05).
The prevalence of was estimated to be low in southern Iran in comparison with previous reports or other developing countries. Preventive strategies with respect to low prevalence rates may be considered in the childhood period.
儿童期被认为是感染……的主要时期。发展中国家的高流行率与胃癌相关。世界不同地区已报告其流行率呈下降趋势。确定流行率对于选择预防策略可能很重要。本研究旨在确定伊朗南部一组儿童中……的流行率，以更新该疾病的当前状况。
这是一项基于人群的横断面研究，于2014年1月至2015年12月在伊朗南部的设拉子进行。纳入了四组人群，包括新生儿、6个月至3岁的儿童、10岁和15岁的儿童。采用多克隆粪便抗体检测进行诊断。
在436名参与者中，24.8%（95%可信区间：20.8 - 29.1）……检测呈阳性：新生儿中为25%（95%可信区间：16.2 - 36.1），6个月至3岁儿童中为22%（95%可信区间：15.2 - 30.2），10岁儿童中为19.5%（95%可信区间：12.3 - 29.4），15岁儿童中为29.2%（95%可信区间：21 - 39）。性别、年龄、兄弟姐妹数量、养宠物情况、父母吸烟状况、父母教育程度、居住地区、出生体重和喂养状况未被发现是……抗原阳性的统计学显著预测因素（P > 0.05）。
与先前报告或其他发展中国家相比，伊朗南部……的流行率估计较低。儿童期可考虑针对低流行率的预防策略。
