Complex Mechanisms of Disease, Aging and Trauma (CMDAT) Research Foundation , Denver, CO, USA.
Imelda GI Clinical Research Centre, Imeldaziekenhuis Bonheiden , Bonheiden, Belgium.
Expert Opin Biol Ther. 2021 Jan;21(1):111-119. doi: 10.1080/14712598.2020.1842355. Epub 2020 Nov 1.
: There are gaps in gastroenterologist team members' understanding of various topics related to biosimilars. We aimed to examine perspectives, views, and attitudes toward biosimilar and shared decision-making (SDM) among gastroenterology team members in Colorado, USA. The ultimate goal was to increase knowledge and awareness of biosimilars and SDM. : We developed educational materials focused on biosimilars and SDM and distributed them to each participating gastroenterology office. Subsequently, we conducted a survey of all team members from participating offices. : Responses were obtained from 54 gastroenterology team members. Most respondents identified the correct answer regarding biosimilars, the nocebo effect, and SDM. Almost half (47.2%) of respondents scored their level of awareness regarding biosimilars prior to reading our educational materials as poor, and nearly one quarter (26.4%) indicated so for SDM. Improvement in scores after reading our materials was significant for both biosimilars and SDM (i.e. biosimilar: z = 6.276, p-value <0.001 and SDM z = 6.328, p-value <0.001). : Educational efforts effectively increased the low baseline knowledge and awareness of biosimilars and SDM among gastroenterology team members. More educational projects focused on biosimilars and SDM are needed to reduce the nocebo effect and prevent hampering of the cost-savings of biosimilars.
: 胃肠病学家团队成员对与生物类似药相关的各种主题的理解存在差距。我们旨在研究美国科罗拉多州胃肠病学团队成员对生物类似药和共同决策 (SDM) 的观点、看法和态度。最终目标是提高对生物类似药和 SDM 的认识和了解。 : 我们开发了专注于生物类似药和 SDM 的教育材料,并分发给每个参与的胃肠病学办公室。随后,我们对参与办公室的所有团队成员进行了调查。 : 共收到 54 名胃肠病学团队成员的回复。大多数受访者正确回答了生物类似药、安慰剂效应和 SDM 的问题。近一半(47.2%)的受访者在阅读我们的教育材料之前表示对生物类似药的了解程度较差,近四分之一(26.4%)的受访者对 SDM 表示如此。阅读我们的材料后,对生物类似药和 SDM 的评分均显著提高(即生物类似药:z = 6.276,p 值<0.001 和 SDM z = 6.328,p 值<0.001)。 : 教育工作有效地提高了胃肠病学团队成员对生物类似药和 SDM 的低基线知识和认识。需要更多专注于生物类似药和 SDM 的教育项目,以减少安慰剂效应并防止阻碍生物类似药的节省成本。