Edwards R G
Physiological Laboratory, University of Cambridge, United Kingdom.
Ann Biol Clin (Paris). 1987;45(3):321-9.
The current clinical status of in vitro fertilization is reviewed including ovarian stimulation, fertilization, implantation after replacement and luteal phase support. The evolution of singleton or multiple pregnancies after IVF is discussed; pregnancy loss can occur after ectopic pregnancy or abortion. Several new scientific advances are described: the cryopreservation of embryos, the studies on the metabolism of embryos by non-invasive methods and the use of fetal tissues to restore abnormal conditions in adults. The current ethical issues of IVF are discussed: freezing of embryos, oocyte and embryo donation, surrogate motherhood as well as the rights of an early embryo and the ethics of embryo research.
本文综述了体外受精的当前临床状况，包括卵巢刺激、受精、胚胎移植后的着床以及黄体期支持。讨论了体外受精后单胎或多胎妊娠的演变；异位妊娠或流产后可能发生妊娠丢失。描述了几项新的科学进展：胚胎冷冻保存、通过非侵入性方法对胚胎代谢的研究以及使用胎儿组织修复成人异常状况。讨论了体外受精当前的伦理问题：胚胎冷冻、卵母细胞和胚胎捐赠、代孕以及早期胚胎的权利和胚胎研究的伦理。
