Nursing Department, University of Valencia, Valencia, Spain.
Cardiology Department, Valladolid University Clinical Hospital, Valladolid, Spain.
J Adv Nurs. 2021 Jan;77(1):286-295. doi: 10.1111/jan.14612. Epub 2020 Oct 27.
The aim of this study was to identify the main medication errors, their causality and the highest risk areas in critical care.
A descriptive, longitudinal and retrospective study.
We performed a systematic analysis of the prescription, transcription and administration records of 2,634 dose units of medications that were administered to a total of 87 critically ill patients during 2018.
Final results have shown important medication errors and a high number of significant drug interactions; prescription phase had the highest mistake rate (71%) and cause of errors (68%); transcription stage had a more variable error typology. A significant correlation was observed between the presence of causes and contributing factors to error during the prescription and the commission of errors during the nurse transcription, being the main risk areas the time of antibiotic administration, dilution errors, concentration and speed of administration of high-risk medications and the technique used for nasogastric tube drug administration.
In critical care, an intolerable number of medication errors are still committed, placing the origin of many of them in the causality and contributing factors identified in the prescription stage.
The origin of many of the medication errors and most interactions is in the prescription stage, being the nurse transcription (nurse intervention) in an important filter that prevents a considerable number of errors from finally reaching the patient. The schedule of administration of time-dependent antibiotics, high-risk medications and the technique of administering medications through a nasogastric tube are important risk areas for the commission of medication errors.
本研究旨在确定重症监护中主要的用药错误、其因果关系和高风险领域。
描述性、纵向和回顾性研究。
我们对 2018 年期间共 87 名危重症患者使用的 2634 个剂量单位的药物的处方、转录和给药记录进行了系统分析。
最终结果显示了重要的用药错误和大量显著的药物相互作用;处方阶段的错误率(71%)和错误原因(68%)最高;转录阶段的错误类型更具变异性。在处方阶段存在导致错误的原因和促成因素与护士转录阶段发生错误之间存在显著相关性,主要的高风险领域包括抗生素给药时间、稀释错误、高危药物的给药浓度和速度以及经鼻胃管给药的技术。
在重症监护中,仍存在大量不可接受的用药错误,其中许多错误的根源在于处方阶段确定的因果关系和促成因素。
许多用药错误和大多数相互作用的根源在于处方阶段,护士转录(护士干预)是一个重要的过滤器,可以防止相当多的错误最终到达患者。时间依赖性抗生素、高危药物的给药时间安排以及经鼻胃管给药的技术是发生用药错误的重要高风险领域。