Paulino Eduardo, de Melo Andreia Cristina, Silva-Filho Agnaldo Lopes, Maciel Luiza de Freitas, Thuler Luiz Claudio Santos, Goss Paul, Nogueira-Rodrigues Angelica
Brazilian National Cancer Institute, Rio de Janeiro, Brazil.
Brazilian Gynecologic Oncology Group, Grupo EVA, Brazil.
JCO Glob Oncol. 2020 Oct;6:1617-1630. doi: 10.1200/GO.20.00099.
Little is known, or has been published previously, regarding consolidated data on the epidemiology of gynecologic cancers (GC) in Brazil. This article describes the incidence, morbidity, and mortality of women in Brazil affected with GC between the years of 2000 and 2017.
Incidence, morbidity, and mortality data from patients with a diagnosis of one out of the five most common GC, cervical (CC), uterine (UC), ovarian (OC), vulvar (VvC), and vaginal (VgC), were obtained from three governmental sources of data.
From 2000 to 2015 CC, OC, and VgC incidence rates (IRs) decreased, whereas the IRs for UC and VvC remained relatively stable. Data from 382,932 women with GC were analyzed. Most patients presented with locally advanced or advanced disease at diagnosis: 60.1% of patients with CC, 31.2% of patients with UC, 67.2% of patients with OC, 45.2% of patients with VvC, and 67.0% of patients with VgC. Time from diagnosis to first treatment was ≥ 60 days in 58.0% of patients with CC, 58.5% of patients with UC, 27.0% of patients with OC, 55.3% of patients with VvC, and 52.7% of patients with VgC. Regarding mortality rates (MRs), with the exception of CC, UC, and VvC, which showed a slight decrease, MRs remained stable between 2000 and 2017.
A comparison with international data indicates that Brazilian patients are diagnosed with more advanced disease and face a longer delay between diagnosis and first treatment. Despite advances in screening and treatment, GC mortality has not decreased satisfactorily in this country.
关于巴西妇科癌症（GC）流行病学的综合数据，此前所知甚少或鲜有发表。本文描述了2000年至2017年间巴西受GC影响女性的发病率、发病率和死亡率。
从三个政府数据来源获取了诊断为五种最常见GC之一（宫颈癌（CC）、子宫癌（UC）、卵巢癌（OC）、外阴癌（VvC）和阴道癌（VgC））患者的发病率、发病率和死亡率数据。
2000年至2015年，CC、OC和VgC的发病率（IRs）下降，而UC和VvC的IRs保持相对稳定。对382,932例GC女性患者的数据进行了分析。大多数患者在诊断时表现为局部晚期或晚期疾病：60.1%的CC患者、31.2%的UC患者、67.2%的OC患者、45.2%的VvC患者和67.0%的VgC患者。58.0%的CC患者、58.5%的UC患者、27.0%的OC患者、55.3%的VvC患者和52.7%的VgC患者从诊断到首次治疗的时间≥60天。关于死亡率（MRs），除CC、UC和VvC略有下降外，2000年至2017年间MRs保持稳定。
与国际数据的比较表明，巴西患者被诊断为更晚期的疾病，并且在诊断和首次治疗之间面临更长的延迟。尽管在筛查和治疗方面取得了进展，但该国GC死亡率并未令人满意地下降。
