Department of Anaesthesia, Max Smart Super Specialty Hospital, Saket, Delhi, India.
Ann Card Anaesth. 2020 Oct-Dec;23(4):383-390. doi: 10.4103/aca.ACA_138_19.
The association with cardiac surgery with cognitive decline was first reported in the 1960s after the introduction of coronary artery surgery. The incidence in cognitive decline was thought to be more after cardiac surgery, especially with the use of the cardiopulmonary bypass. Anesthesia and surgery are both associated with cognitive decline but many other factors appear to contribute its genesis. On-pump surgery, microembolization during manipulation of the heart and great vessels, temperature changes, pH changes, and altered cerebral perfusion, during cardiac surgery, have all been blamed for this. Postoperative cognitive decline is associated with poor clinical outcomes and higher mortality. Several studies have been conducted in the last decade to determine the genesis of this malady. Current evidence is absolving cardiac surgery and anesthesia to be the primary causes per se of cognitive dysfunction.
心脏手术与认知能力下降的关联最早是在 20 世纪 60 年代冠状动脉手术引入后报道的。人们认为心脏手术后认知能力下降的发生率更高,尤其是在使用体外循环的情况下。麻醉和手术都会导致认知能力下降,但许多其他因素似乎也促成了其发生。心脏手术期间,体外循环、心脏和大血管操作时的微栓塞、温度变化、pH 值变化以及脑灌注改变等因素都被归咎于此。术后认知能力下降与不良临床结局和更高的死亡率有关。过去十年进行了多项研究以确定这种疾病的病因。目前的证据表明,心脏手术和麻醉本身并不是认知功能障碍的主要原因。