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经食管探头放置会增加气管内导管套囊压力,但与先天性心脏手术后的术后拔管失败无关。

Transesophageal probe placement increases endotracheal tube cuff pressure but is not associated with postoperative extubation failure after congenital cardiac surgery.

机构信息

Department of Anaesthesiology and Perioperative Medicine, Division of Paediatric Anaesthesiology, University of Pittsburgh School of Medicine, USA.

出版信息

Ann Card Anaesth. 2020 Oct-Dec;23(4):447-452. doi: 10.4103/aca.ACA_143_19.

Abstract

CONTEXT

The concomitant use of cuffed endotracheal tubes (ETT) and transesophageal echocardiography (TEE) probes increases ETT cuff pressures (CP), which may contribute to mucosal ischemia and perioperative complications such as failed extubation.

AIMS

To assess changes in ETT CP after TEE insertion in patients of different age groups undergoing congenital heart surgery and examine the relationship between ETT CP and postoperative extubation failure.

SETTINGS AND DESIGN

Single-center quality improvement project.

SUBJECTS AND METHODS

ETT CP was measured with a manometer following intubation and again after TEE insertion. Tracheal perfusion pressure was then calculated and postoperative extubation failures were recorded.

STATISTICAL ANALYSIS

Chi-square testing, Fisher's-exact testing, one-way analysis of variance testing or Kruskal-Wallis testing with Dunn's pairwise, and student's t-test or Wilcoxon rank-sum testing were used to analyze the data.

RESULTS

Median ETT CP increased significantly after TEE insertion in each age group, with infants showing a smaller magnitude of increase (+2 [1-6] cm HO, P < 0.001) than adults (+12 [8-14] cm HO, P = 0.008) (intergroup comparison P = 0.002). Five patients (9%) failed extubation, all of which were infants. Within the infant subgroup, no significant difference existed between failed vs successful extubation regarding ETT CP during bypass (15 ± 1 vs 16 ± 2 mmHg, P = 0.206) or tracheal perfusion pressure pre-bypass (34 ± 9 vs 38 ± 11 mmHg, P = 0.518), during bypass (20 ± 9 vs 22 ± 6 mmHg, P = 0.697), or post-bypass (42 ± 9 vs 41 ± 9 mmHg, P = 0.923). There was a significant difference in cardiopulmonary bypass duration (151 ± 29 vs 85 ± 32 min, P < 0.001).

CONCLUSION

Factors beyond intraoperative ETT CP likely play a larger role in postoperative extubation failure.

摘要

背景

使用带套囊的气管内导管(ETT)和经食管超声心动图(TEE)探头会增加 ETT 套囊压力(CP),这可能导致黏膜缺血和围手术期并发症,如拔管失败。

目的

评估不同年龄组接受先天性心脏手术的患者在 TEE 插入后 ETT CP 的变化,并检查 ETT CP 与术后拔管失败之间的关系。

设置和设计

单中心质量改进项目。

受试者和方法

在插管后和 TEE 插入后使用压力计测量 ETT CP,然后计算气管灌注压并记录术后拔管失败。

统计分析

使用卡方检验、Fisher 精确检验、单向方差分析检验或 Kruskal-Wallis 检验加 Dunn 两两比较、学生 t 检验或 Wilcoxon 秩和检验来分析数据。

结果

在每个年龄组中,TEE 插入后 ETT CP 均显著增加,婴儿的增加幅度较小(+2 [1-6] cm HO,P < 0.001),而成人的增加幅度较大(+12 [8-14] cm HO,P = 0.008)(组间比较 P = 0.002)。有 5 名患者(9%)拔管失败,均为婴儿。在婴儿亚组中,在体外循环期间,失败与成功拔管的 ETT CP 无显著差异(15 ± 1 与 16 ± 2 mmHg,P = 0.206)或体外循环前的气管灌注压(34 ± 9 与 38 ± 11 mmHg,P = 0.518)、体外循环期间(20 ± 9 与 22 ± 6 mmHg,P = 0.697)或体外循环后(42 ± 9 与 41 ± 9 mmHg,P = 0.923)。体外循环持续时间有显著差异(151 ± 29 与 85 ± 32 min,P < 0.001)。

结论

术中 ETT CP 以外的因素可能在术后拔管失败中起更大作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ecf/7879897/1a181a2d1597/ACA-23-447-g001.jpg

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