Calder Alyson, Hegarty Mary, Erb Thomas O, von Ungern-Sternberg Britta S
Department of Anaesthesia and Pain Management, Princess Margaret Hospital for Children, Perth, Australia.
Paediatr Anaesth. 2012 Mar;22(3):239-43. doi: 10.1111/j.1460-9592.2011.03727.x. Epub 2011 Nov 8.
The incidence of postoperative sore throat (POST) following intubation is not well defined in the pediatric population. The etiology is multifactorial and includes impairment of subglottic mucosal perfusion and edema as a result of the pressures exerted by cuffed or uncuffed tubes.
To determine the incidence of, and risk factors for, POST in intubated children undergoing elective day-case surgery.
Five hundred patients aged 3-16 years were studied prospectively. Endotracheal tube (ETT) choice (cuffed or uncuffed) was left to the anesthetist. The cuff was inflated either until loss of audible leak or to a determined pressure using a cuff manometer. The research team then measured the cuff pressure (CP). POST incidence and intensity was determined by interviewing patients prior to discharge from the same day procedure unit. Chi-square testing and stepwise logistic regression were used to determine the predictors of POST.
Of the 111 (22%) children developed a sore throat, 19 (3.8%) a sore neck, and 5 (1%) a sore jaw. 19% of patients with cuffed ETTs complained of sore throat compared with 37% of those intubated with an uncuffed ETT. The incidence of POST increased with CP; 0-10% at 0 cmH(2)O, 4% at 11-20 cmH(2)O, 20% at 21-30 cmH(2)O, 68% at CP 31-40 cmH(2)O, and 96% at CP >40 cmH(2)O. The ETT CP and use of uncuffed ETTs were univariate predictors of POST.
Children intubated with uncuffed ETTs are more likely to have POST. ETT CP is positively correlated with the incidence of POST. When using cuffed ETTs, CP should be routinely measured intraoperatively.
小儿群体中插管后咽痛(POST)的发生率尚不明确。其病因是多因素的,包括带套囊或不带套囊的气管导管所施加的压力导致声门下黏膜灌注受损和水肿。
确定接受择期日间手术的插管儿童中POST的发生率及危险因素。
对500例3 - 16岁患者进行前瞻性研究。气管内导管(ETT)的选择(带套囊或不带套囊)由麻醉师决定。套囊充气直至听不到漏气声,或使用套囊压力计将其充至确定压力。研究团队随后测量套囊压力(CP)。通过在当日手术病房出院前对患者进行访谈来确定POST的发生率和严重程度。采用卡方检验和逐步逻辑回归来确定POST的预测因素。
111例(22%)儿童出现咽痛,19例(3.8%)颈部疼痛,5例(1%)颌部疼痛。使用带套囊ETT的患者中有19%抱怨咽痛,而使用不带套囊ETT插管的患者中这一比例为37%。POST的发生率随CP升高而增加;CP为0 cmH₂O时为0 - 10%,11 - 20 cmH₂O时为4%,21 - 30 cmH₂O时为